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[水凝胶的性质及其在生物医学中的应用]

[Properties of Hydrogel and Its Applications in Biomedicine].

作者信息

Ge Li, Liu Liwei, Jiang Lina, Song Wengang

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2015 Dec;32(6):1369-73.

Abstract

Hydrogel is a creative polymeric biomaterial which can resemble extracellular matrix (ECM) in vitro. Hydrogel is also a material with intrinsic bioinert, but it can offer mechanical support and developmental guide for cell growth and new tissue organization by designing physicochemical and biological properties of hydrogels precisely. This review mainly introduces design of hydrogels, properties and applications in tissue engineering and regenerative medicine, drug delivery, stem cell culture and cell therapy.

摘要

水凝胶是一种具有创新性的聚合生物材料,在体外可类似于细胞外基质(ECM)。水凝胶也是一种具有内在生物惰性的材料,但通过精确设计水凝胶的物理化学和生物学特性,它可为细胞生长和新组织构建提供机械支持和发育引导。本综述主要介绍水凝胶的设计、特性及其在组织工程与再生医学、药物递送、干细胞培养和细胞治疗中的应用。

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