Institute for Developmental Genetics, Heinrich-Heine University, D-40225 Düsseldorf, Germany.
Institute for Developmental Genetics, Heinrich-Heine University, D-40225 Düsseldorf, Germany.
Trends Plant Sci. 2016 May;21(5):373-375. doi: 10.1016/j.tplants.2016.03.002. Epub 2016 Apr 11.
Formative cell divisions generate new cell types and tissues during development, and are controlled by receptor kinase signalling pathways. The phosphatase PP2A has now been shown to be both a target and positive regulator of the receptor kinase ACR4, thus creating a feed-forward loop that serves to establish new cell fates.
有丝分裂产生新的细胞类型和组织在发展过程中,并受受体激酶信号通路的控制。现在已经表明,磷酸酶 PP2A 既是受体激酶 ACR4 的靶标又是其正调节剂,从而形成正向反馈环,有助于建立新的细胞命运。