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小儿创伤性开放性眼球损伤:一种新型预后评分的特征分析

Traumatic open globe injury in young pediatric patients: characterization of a novel prognostic score.

作者信息

Read Sarah P, Cavuoto Kara M

机构信息

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.

出版信息

J AAPOS. 2016 Apr;20(2):141-4. doi: 10.1016/j.jaapos.2015.11.008.

Abstract

BACKGROUND

Open globe injury is a common cause of monocular blindness in children. Current formulas to predict outcomes of open globe injury often rely heavily on visual acuity and presence of an afferent pupillary defect, examination elements that are difficult to assess in young children. We aimed to analyze the features of open globe injuries in children aged 0-6 years to facilitate development of a novel algorithm for predicting visual outcomes in this age group.

METHODS

The medical records of patients 0-6 years of age presenting at a single institution with open globe injury from 2000 to 2013 were retrospectively reviewed. Epidemiology, physical examination, and intervention data were used to develop a prognostic algorithm.

RESULTS

A total of 28 patients were included. Mean age at presentation was 4.2 years (range, 1.9-6.7). Glass was the most common mechanism of injury. Associated findings included uveal prolapse (93%), choroidal detachment (39%), hyphema (32%), and retinal detachment (11%). In addition to primary repair, 43% patients required a lensectomy, and 7% underwent surgery to repair retinal detachment. Complicating cataract (P < 0.005) and a wound >6 mm (P < 0.05) were associated with a final visual acuity worse than 20/40. A novel algorithm for predicting visual outcome was devised with a sensitivity of 81% and a specificity of 92%.

CONCLUSIONS

Patients 0-6 years of age with open globe injuries present unique risk factors for poor outcome. The trauma score generated by our algorithm is not reliant on presenting visual acuity and may be useful in predicting prognosis in very young children.

摘要

背景

开放性眼球损伤是儿童单眼失明的常见原因。目前用于预测开放性眼球损伤预后的公式通常严重依赖视力和传入性瞳孔障碍的存在,而这些检查项目在幼儿中很难评估。我们旨在分析0至6岁儿童开放性眼球损伤的特征,以促进开发一种预测该年龄组视力预后的新算法。

方法

回顾性分析2000年至2013年在单一机构就诊的0至6岁开放性眼球损伤患者的病历。流行病学、体格检查和干预数据用于开发一种预后算法。

结果

共纳入28例患者。就诊时的平均年龄为4.2岁(范围1.9至6.7岁)。玻璃是最常见的致伤机制。相关表现包括葡萄膜脱垂(93%)、脉络膜脱离(39%)、前房积血(32%)和视网膜脱离(11%)。除了一期修复外,43%的患者需要进行晶状体切除术,7%的患者接受了视网膜脱离修复手术。并发白内障(P < 0.005)和伤口>6mm(P < 0.05)与最终视力低于20/40相关。设计了一种预测视力预后的新算法,其灵敏度为81%,特异性为92%。

结论

0至6岁的开放性眼球损伤患者存在预后不良的独特危险因素。我们的算法产生的创伤评分不依赖于就诊时的视力,可能有助于预测幼儿的预后。

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