Carlisle L, Forge A
Electron Microscopy Unit, Institute of Laryngology and Otology, London, U.K.
Hear Res. 1989 Mar;38(1-2):111-7. doi: 10.1016/0378-5955(89)90132-9.
The stria vascularis (SV) was quantitatively compared in three species commonly used in auditory research: guinea pig, mouse and gerbil. Measurements were obtained for surface area, cross-sectional area, length, width and thickness of SV. Surface area and length were proportional to the overall size of the cochlea in each species, but there was no significant difference between species in mean cross-sectional area. In guinea pig and mouse, there was no significant difference in thickness (endolymphatic surface to spiral ligament) and a similar pattern was observed for width (Reissner's membrane to spiral prominence): the width of SV increased from the apical end to a point 80% of the distance from the apex, then decreased to the basal end of SV. The thickness of gerbil SV was significantly less (P less than 0.001) and there was less of a gradient in width as compared to guinea pig and mouse. The vessels of SV were compared in terms of vascular density (vessels per unit area), rbc density (red blood cells per unit area), R/V (rbc density/vascular density), inter-vessel spacing and vessel diameter. Highly significant (P less than 0.001) differences between species were found in vascular density, RBC density and vessel diameter, but there were no differences between species for R/V or inter-vessel spacing. The results of this study may reflect differences in the metabolic requirements of SV among different species.
对听觉研究中常用的三种物种（豚鼠、小鼠和沙鼠）的血管纹（SV）进行了定量比较。测量了血管纹的表面积、横截面积、长度、宽度和厚度。表面积和长度与每个物种耳蜗的整体大小成正比，但各物种之间的平均横截面积没有显著差异。在豚鼠和小鼠中，厚度（内淋巴表面至螺旋韧带）没有显著差异，宽度（Reissner膜至螺旋隆起）也观察到类似模式：血管纹的宽度从顶端开始增加至距顶端80%的位置，然后向血管纹的基部末端减小。沙鼠血管纹的厚度显著更小（P小于0.001），与豚鼠和小鼠相比，宽度的梯度也更小。对血管纹的血管在血管密度（每单位面积的血管数）、红细胞密度（每单位面积的红细胞数）、R/V（红细胞密度/血管密度）、血管间距和血管直径方面进行了比较。发现各物种之间在血管密度、红细胞密度和血管直径方面存在高度显著（P小于0.001）的差异，但在R/V或血管间距方面各物种之间没有差异。本研究结果可能反映了不同物种血管纹代谢需求的差异。
