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声诱发橄榄耳蜗反馈的快速评估:对侧声音对复合动作电位的抑制作用

Rapid assessment of sound-evoked olivocochlear feedback: suppression of compound action potentials by contralateral sound.

作者信息

Liberman M C

机构信息

Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts.

出版信息

Hear Res. 1989 Mar;38(1-2):47-56. doi: 10.1016/0378-5955(89)90127-5.

DOI:10.1016/0378-5955(89)90127-5
PMID:2708159
Abstract

The compound action potential (CAP) measured at the round window of anesthetized cats in response to low-level tone pips can be significantly suppressed by addition of tones or noise to the opposite ear. This contralateral-sound suppression disappears upon transection of the olivocochlear bundle. The frequency and level dependence of the suppression phenomenon are well explained by known sound-evoked discharge properties of single olivocochlear neurons. Thus, the contralateral-sound suppression of cochlear CAP should prove useful as a rapid measure of the magnitude of the sound-evoked efferent feedback to the cochlea.

摘要

在麻醉猫的圆窗处测量到的复合动作电位(CAP),对低强度纯音短声的反应,可通过在对侧耳添加纯音或噪声而被显著抑制。这种对侧声音抑制在切断橄榄耳蜗束后消失。已知单个橄榄耳蜗神经元的声音诱发放电特性很好地解释了抑制现象的频率和强度依赖性。因此,耳蜗CAP的对侧声音抑制应可作为一种快速测量声音诱发的传出反馈至耳蜗大小的有用方法。

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