Cohen G, Henderson-Smart D J
Department of Perinatal Medicine, King George V Hospital, Camperdown, New South Wales, Australia.
J Appl Physiol (1985). 1989 Mar;66(3):1328-35. doi: 10.1152/jappl.1989.66.3.1328.
Submental electromyorgams (SM EMG) were recorded from 20 preterm babies (gestational age 30 +/- 2 wk, postmenstrual age at study 35 +/- 2 wk) (mean +/- SD) and 3 full-term infants (7-14 days old). SM EMG was evaluated during eupnea and brief experimental airway occlusion. Phasic inspiratory SM EMG was rarely seen during eupnea. SM EMG tended to increase on the first occluded effort, although this increase was not statistically significant in most babies. All infants showed progressive breath-by-breath augmentation of phasic SM EMG during occlusions in rapid-eye-movement (REM) as well as quiet (QS) sleep; phasic increases in SM EMG were similar during REM and QS occlusions in the majority (16/22) of babies. Periods of airway closure were detected during 24 occlusions in 5 infants; phasic SM EMG was reduced on these occasions. The results are consistent with the idea that recruitment of upper airway muscles contributes to the stability of the airway of the preterm human.
对20名早产儿(胎龄30±2周,研究时的月经后年龄为35±2周)(均值±标准差)和3名足月儿(7 - 14日龄)记录颏下肌肌电图(SM EMG)。在平静呼吸和短暂的实验性气道阻塞期间评估SM EMG。在平静呼吸期间很少见到阶段性吸气SM EMG。在第一次阻塞用力时,SM EMG往往会增加,尽管在大多数婴儿中这种增加没有统计学意义。在快速眼动(REM)睡眠以及安静(QS)睡眠期间的阻塞过程中,所有婴儿的阶段性SM EMG均逐次呼吸进行性增强;在大多数(16/22)婴儿中,REM睡眠和QS睡眠期间阻塞时SM EMG的阶段性增加相似。在5名婴儿的24次阻塞期间检测到气道关闭期;在此期间阶段性SM EMG降低。这些结果与上气道肌肉的募集有助于早产人类气道稳定性的观点一致。