Christel P, Meunier A, Heller M, Torre J P, Peille C N
Laboratoire de Recherches Orthopédiques-U.A.-C.N.R.S., Faculté de Médecine, Paris, France.
J Biomed Mater Res. 1989 Jan;23(1):45-61. doi: 10.1002/jbm.820230105.
Yttrium-oxide-partially-stabilized zirconia (YPSZ) belongs to a new class of ceramics exhibiting an improved toughness when compared to alumina. The toughening mechanism is related to a martensitic-like transformation of tetragonal metastable grains into a monoclinic state occurring at the crack tip. Specific tests showed that YPSZ exhibited a high bending strength (900-1200 MPa), a low Young's modulus (200 GPa), and a high toughness (KIC = 9-10 MN/m3/2). Its average grain size of 0.5 microns allows a surface roughness as low as 0.008 microns. Sterilization or aging in saline solution at room temperature for 100 days did not affect the toughness of this material. Cylindrical YPSZ samples, manufactured by cold isostatic pressing and sintering, were implanted in the paraspinal muscles in the rat up to 12 weeks. The tissue reaction was evaluated with reference to alumina (ISO requirements) by means of quantitative histomorphometry. No significant differences were found between YPSZ and alumina for both the membrane thickness and cell distributions surrounding the implants.
钇氧化物部分稳定氧化锆（YPSZ）属于一类新型陶瓷，与氧化铝相比，其韧性有所提高。增韧机制与裂纹尖端四方亚稳晶粒向单斜晶态的马氏体样转变有关。具体测试表明，YPSZ具有较高的弯曲强度（900 - 1200兆帕）、较低的杨氏模量（200吉帕）和较高的韧性（断裂韧性KIC = 9 - 10兆牛/米³/²）。其平均晶粒尺寸为0.5微米，可使表面粗糙度低至0.008微米。在室温下于盐溶液中进行100天的灭菌或老化处理不会影响该材料的韧性。通过冷等静压和烧结制造的圆柱形YPSZ样品被植入大鼠脊柱旁肌肉中长达12周。通过定量组织形态计量学，参照氧化铝（ISO要求）评估组织反应。在植入物周围的膜厚度和细胞分布方面，YPSZ和氧化铝之间未发现显著差异。
