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OPAT for cellulitis: its benefits and the factors that predispose to longer treatment.

作者信息

Zhang J, Moore E, Bousfield R

机构信息

School of Clinical Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0SP, UK.

Department of Infectious Diseases, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK.

出版信息

Eur J Clin Microbiol Infect Dis. 2016 Jun;35(6):1013-5. doi: 10.1007/s10096-016-2631-y. Epub 2016 Apr 15.

DOI:10.1007/s10096-016-2631-y
PMID:27084095
Abstract

This retrospective study investigated the demographics and treatment outcomes of patients with cellulitis receiving outpatient parenteral antibiotic therapy (OPAT) between 2010 and 2014 in Cambridge University Hospitals. The rate of treatment failure (as indicated by the readmission to hospital) was low, at 5.5%. Risk factors associated with a longer duration of OPAT treatment included: immunosuppression, peripheral vascular disease, obesity, lymphoedema, previous cellulitis and diabetes.

摘要

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本文引用的文献

1
Outpatient parenteral antibiotic therapy: principles and practice.门诊患者的肠外抗生素治疗:原则与实践。
Eur J Intern Med. 2013 Oct;24(7):617-23. doi: 10.1016/j.ejim.2013.03.014. Epub 2013 Apr 18.
2
Risk factors for clinical failure in patients hospitalized with cellulitis and cutaneous abscess.住院治疗蜂窝织炎和皮肤脓肿患者临床治疗失败的风险因素。
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Risk stratification and outcome of cellulitis admitted to hospital.住院患者蜂窝织炎的风险分层和结局。
Current practices and challenges of outpatient parenteral antimicrobial therapy: a narrative review.
门诊患者的肠外抗菌治疗的现状和挑战:叙事性综述。
J Antimicrob Chemother. 2024 Sep 3;79(9):2083-2102. doi: 10.1093/jac/dkae177.
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Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infection in Patients With Obesity or Diabetes: A Subgroup Analysis of Pooled Phase 3 Clinical Trials.达巴万星用于治疗肥胖或糖尿病患者的急性细菌性皮肤和皮肤结构感染:3期汇总临床试验的亚组分析
Open Forum Infect Dis. 2023 May 9;10(6):ofad256. doi: 10.1093/ofid/ofad256. eCollection 2023 Jun.
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Risk of Treatment Failure for Prosthetic Joint Infections: Retrospective Chart Review in an Outpatient Parenteral Antimicrobial Therapy Program.人工关节感染治疗失败的风险:门诊肠外抗菌治疗项目中的回顾性病历审查
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Treatment failure definitions for non-purulent skin and soft tissue infections: a systematic review.非化脓性皮肤及软组织感染的治疗失败定义:系统评价。
Infection. 2020 Feb;48(1):75-83. doi: 10.1007/s15010-019-01347-w. Epub 2019 Aug 5.
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Metabolic Obesity Phenotypes and Risk of Cellulitis: A Cohort Study.代谢性肥胖表型与蜂窝织炎风险:一项队列研究。
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J Infect. 2010 Jun;60(6):431-9. doi: 10.1016/j.jinf.2010.03.014. Epub 2010 Mar 25.
4
Baseline factors predicting the duration of intravenous antibiotic therapy for cellulitis in an outpatient setting.预测门诊蜂窝织炎患者静脉抗生素治疗疗程的基线因素。
Eur J Clin Microbiol Infect Dis. 2010 Mar;29(3):347-9. doi: 10.1007/s10096-009-0855-9.
5
Establishment of an outpatient and home parenteral antimicrobial therapy service at a London teaching hospital: a case series.伦敦一家教学医院门诊及家庭肠外抗菌治疗服务的建立:病例系列研究
J Antimicrob Chemother. 2009 Sep;64(3):630-4. doi: 10.1093/jac/dkp212. Epub 2009 Jun 23.
6
Lymphoedema and cellulitis: chicken or egg?淋巴水肿与蜂窝织炎:孰因孰果?
Br J Dermatol. 2008 Jun;158(6):1175-6. doi: 10.1111/j.1365-2133.2008.08590.x.
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Ethnicity and other risk factors for acute lower limb cellulitis: a U.K.-based prospective case-control study.急性下肢蜂窝织炎的种族及其他风险因素:一项基于英国的前瞻性病例对照研究。
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