猪圆环病毒2型亚病毒DNA分子的完整核苷酸序列
Complete nucleotide sequence of a subviral DNA molecule of porcine circovirus type 2.
作者信息
Wen Han
机构信息
Department of Information Engineering, HeFei University of Technology, Xuancheng, 242000, China.
出版信息
Arch Virol. 2016 Jul;161(7):2037-8. doi: 10.1007/s00705-016-2859-y. Epub 2016 Apr 15.
Porcine circovirus type 2 (PCV2) is a member of the genus Circovirus in the family Circoviridae. Most subgenomic molecules of PCV2 have been mapped. Here, the first full-length sequence of a subviral molecule of PCV2 (CH-IVT12) containing a reverse complement sequence of the PCV2 genome was determined by sequencing DNA extracted from PK15 cells infected with PCV2. The circular CH-IVT12 DNA consists of 1136 nucleotides and contains one major open reading frame.
猪圆环病毒2型（PCV2）是圆环病毒科圆环病毒属的成员。PCV2的大多数亚基因组分子已被定位。在此，通过对从感染PCV2的PK15细胞中提取的DNA进行测序，确定了PCV2亚病毒分子（CH-IVT12）的首个全长序列，该序列包含PCV2基因组的反向互补序列。环状的CH-IVT12 DNA由1136个核苷酸组成，包含一个主要的开放阅读框。
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