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预防克罗恩病术后复发的实用方法

A Practical Approach to Preventing Postoperative Recurrence in Crohn's Disease.

作者信息

Hashash Jana G, Regueiro Miguel

机构信息

Division of Gastroenterology, Hepatology, and Nutrition, University of Pittsburgh School of Medicine, University of Pittsburgh Medical Center, Mezzanine Level, C Wing, 200 Lothrop Street, Pittsburgh, PA, 15213, USA.

出版信息

Curr Gastroenterol Rep. 2016 May;18(5):25. doi: 10.1007/s11894-016-0499-8.

DOI:10.1007/s11894-016-0499-8
PMID:27086006
Abstract

Postoperative Crohn's disease recurrence remains common, and preventing additional surgery remains a challenge. A critical step to postoperative management of Crohn's disease is being able to identify patients who should receive immediate postoperative therapy from the patients who can wait for recurrence prior to starting medications. All patients, regardless of their risk for recurrence, are advised to undergo a colonoscopy at 6 to 12 months after surgery to evaluate for endoscopic evidence of Crohn's disease. Further management of patients depends on symptoms and the presence or absence of endoscopic recurrence.

摘要

克罗恩病术后复发仍然很常见,避免再次手术仍是一项挑战。克罗恩病术后管理的关键一步是能够区分哪些患者应在术后立即接受治疗,哪些患者可以等待复发后再开始用药。建议所有患者,无论复发风险如何,在术后6至12个月接受结肠镜检查,以评估克罗恩病的内镜证据。对患者的进一步管理取决于症状以及内镜复发的有无。

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1
A Practical Approach to Preventing Postoperative Recurrence in Crohn's Disease.预防克罗恩病术后复发的实用方法
Curr Gastroenterol Rep. 2016 May;18(5):25. doi: 10.1007/s11894-016-0499-8.
2
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3
The evolving management of postoperative Crohn's disease.术后克罗恩病的治疗进展。
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4
In favour of prophylactic treatment for post-operative recurrence in Crohn's disease.支持对克罗恩病术后复发进行预防性治疗。
Ital J Gastroenterol Hepatol. 1998 Apr;30(2):219-25.
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Health Maintenance for Adult Patients with Inflammatory Bowel Disease.成年炎症性肠病患者的健康维护
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本文引用的文献

1
Adalimumab is more effective than azathioprine and mesalamine at preventing postoperative recurrence of Crohn's disease: a randomized controlled trial.阿达木单抗在预防克罗恩病术后复发方面比巯嘌呤和美沙拉嗪更有效:一项随机对照试验。
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术后克罗恩病管理中的知识差距:一项美国全国性调查。
Dig Dis Sci. 2018 Jan;63(1):53-60. doi: 10.1007/s10620-017-4844-z. Epub 2017 Nov 17.
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CT Enterography for Surveillance of Anastomotic Recurrence within 12 Months of Bowel Resection in Patients with Crohn's Disease: An Observational Study Using an 8-Year Registry.CT小肠造影用于克罗恩病患者肠道切除术后12个月内吻合口复发监测:一项基于8年登记数据的观察性研究
Korean J Radiol. 2017 Nov-Dec;18(6):906-914. doi: 10.3348/kjr.2017.18.6.906. Epub 2017 Sep 21.
The evolving management of postoperative Crohn's disease.
术后克罗恩病的治疗进展。
Expert Rev Gastroenterol Hepatol. 2012 Sep;6(5):637-48. doi: 10.1586/egh.12.45.
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Adalimumab in prevention of postoperative recurrence of Crohn's disease in high-risk patients.阿达木单抗预防高危患者克罗恩病术后复发。
World J Gastroenterol. 2012 Aug 28;18(32):4391-8. doi: 10.3748/wjg.v18.i32.4391.
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Adalimumab for the prevention and/or treatment of post-operative recurrence of Crohn's disease: a prospective, two-year, single center, pilot study.阿达木单抗预防和/或治疗克罗恩病术后复发的前瞻性、为期两年、单中心、初步研究。
J Crohns Colitis. 2012 Oct;6(9):924-31. doi: 10.1016/j.crohns.2012.02.012. Epub 2012 Mar 15.
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Prevention of postoperative recurrence of Crohn's disease by Adalimumab: a case series.阿达木单抗预防克罗恩病术后复发:病例系列。
Eur J Gastroenterol Hepatol. 2012 Apr;24(4):468-70. doi: 10.1097/MEG.0b013e3283500849.
7
Scheduled infliximab monotherapy to prevent recurrence of Crohn's disease following ileocolic or ileal resection: a 3-year prospective randomized open trial.经预定安排的英夫利昔单抗单药疗法用于预防回肠结肠切除术或回肠切除术治疗后的克罗恩病复发:一项 3 年前瞻性随机开放试验。
Inflamm Bowel Dis. 2012 Sep;18(9):1617-23. doi: 10.1002/ibd.21928. Epub 2011 Nov 13.
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Postoperative recurrent luminal Crohn's disease: a systematic review.术后复发性腔型克罗恩病:系统综述。
Inflamm Bowel Dis. 2012 Apr;18(4):758-77. doi: 10.1002/ibd.21825. Epub 2011 Aug 9.
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Postoperative Crohn's disease: how can we prevent it?术后克罗恩病:我们如何预防?
Expert Rev Clin Immunol. 2010 Jul;6(4):501-4. doi: 10.1586/eci.10.33.
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Management and prevention of postoperative Crohn's disease.术后克罗恩病的管理与预防
Inflamm Bowel Dis. 2009 Oct;15(10):1583-90. doi: 10.1002/ibd.20909.