Senda Joe, Nishikawa Tomohide, Iizuka Hiroshi, Kato Naoki, Ito Hiroshi, Ohshima Ryosuke, Yamamoto Takashi, Kato Takenori, Hasegawa Toshinori, Izumi Takashi, Wakabayashi Toshihiko
Department of Neurology and Rehabilitation, Komaki City Hospital, Japan.
Intern Med. 2016;55(8):985-9. doi: 10.2169/internalmedicine.55.6096. Epub 2016 Apr 15.
A 41-year-old woman was admitted due to a sudden-onset severe headache, left hemiparesis and dysarthria. Diffusion-weighted magnetic resonance imaging showed an acute infarct in the bilateral pons, and magnetic resonance angiography revealed basilar artery (BA) occlusion resulting from dissection of the right vertebral artery (VA). She was treated with intravenous recombinant tissue plasminogen activator (rt-PA) 110 minutes after symptom onset. Subsequently, brain angiography was performed along with mechanical thrombolysis using Trevo ProVue retriever devices. The BA was successfully recanalized 240 minutes after the onset of symptoms. Thrombectomy is a promising treatment strategy for cases of VA dissection resistant to intravenous rt-PA thrombolysis.
一名41岁女性因突发剧烈头痛、左侧偏瘫和构音障碍入院。弥散加权磁共振成像显示双侧脑桥急性梗死,磁共振血管造影显示右侧椎动脉夹层导致基底动脉闭塞。症状发作110分钟后,她接受了静脉注射重组组织型纤溶酶原激活剂(rt-PA)治疗。随后,进行了脑血管造影,并使用Trevo ProVue取栓装置进行了机械溶栓。症状发作240分钟后,基底动脉成功再通。对于静脉rt-PA溶栓治疗无效的椎动脉夹层病例,血栓切除术是一种有前景的治疗策略。