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加氏乳球菌引起的无发热性多瓣膜感染性心内膜炎:一例报告及文献综述

Afebrile Multi-valve Infective Endocarditis Caused by Lactococcus garvieae: A Case Report and Literature Review.

作者信息

Suh Yooseok, Ja Kim Min, Seung Jung Jae, Pil Chong Yong, Hwan Kim Chul, Kang Youngjin, Wook Sohn Jang, Kyung Yoon Young

机构信息

Division of Infectious Diseases, Department of Internal Medicine, University of Ulsan College of Medicine, Korea.

出版信息

Intern Med. 2016;55(8):1011-5. doi: 10.2169/internalmedicine.55.5935. Epub 2016 Apr 15.

Abstract

Lactococcus garvieae is considered to be a rare pathogen with low virulence in humans. We herein experienced an unusual case of multi-valve infective endocarditis caused by L. garvieae in an elderly woman who had undergone bioprosthetic mitral valve replacement due to severe mitral stenosis with rheumatic etiology. The patient was successfully treated with cardiac surgery after teicoplanin antimicrobial therapy failure followed by ceftriaxone treatment. L. garvieae was confirmed as the pathogen through 16S rRNA sequencing. To the best of our knowledge, this is the first case to indicate an effective treatment for infective endocarditis caused by L. garvieae in the Republic of Korea.

摘要

加氏乳球菌被认为是一种在人类中致病性较低的罕见病原体。我们在此报告一例不寻常的多瓣膜感染性心内膜炎病例,该病例由加氏乳球菌引起,患者为一名老年女性,因风湿性病因导致严重二尖瓣狭窄,已接受生物人工二尖瓣置换术。在替考拉宁抗菌治疗失败后改用头孢曲松治疗,随后患者通过心脏手术成功治愈。通过16S rRNA测序确认加氏乳球菌为病原体。据我们所知,这是韩国首例显示对加氏乳球菌引起的感染性心内膜炎进行有效治疗的病例。

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