Lim Felicia H, Jenkins David R
Clinical Microbiology, University Hospitals of Leicester NHS Trust, Leicester, UK.
BMJ Case Rep. 2017 May 22;2017:bcr-2017-220116. doi: 10.1136/bcr-2017-220116.
A 57-year-old man presented with native mitral valve endocarditis caused by , a known animal pathogen that is increasingly being reported as a cause of human infections. The organism was cultured in four sets of blood cultures and identification was initially made by matrix-assisted laser desorption/ionisation-time of flight mass spectrometry and confirmed by 16S rDNA PCR of the blood culture isolate. He was successfully treated with 6 weeks of both amoxicillin and gentamicin and underwent valve replacement surgery after 4 weeks of antimicrobial treatment. The removed valve was sterile but DNA was detected on the valve using 16S rDNA PCR. The cause of the infection could not be ascertained but flexible sigmoidoscopy demonstrated colonic polyps, which have been linked to infection with this organism.
一名57岁男性因感染 （一种已知的动物病原体，越来越多地被报道为人类感染的病因） 而出现自体二尖瓣心内膜炎。该病原体在四组血培养中培养出来，最初通过基质辅助激光解吸/电离飞行时间质谱进行鉴定，并通过血培养分离株的16S rDNA PCR得到确认。他接受了6周的阿莫西林和庆大霉素联合治疗，并在抗菌治疗4周后接受了瓣膜置换手术。切除的瓣膜无菌，但使用16S rDNA PCR在瓣膜上检测到了 DNA。 感染的原因无法确定，但乙状结肠镜检查显示有结肠息肉，这与该病原体感染有关。
