Khan Wajid, Bakht Jehan, Shafi Mohammad
Institute of Biotechnology and Genetic Engineering, The University of Agriculture Peshawar, KPK, Pakistan.
Department of Agronomy, The University of Agriculture Peshawar, KPK, Pakistan.
Pak J Pharm Sci. 2016 Mar;29(2):467-75.
The present study investigates the antimicrobial activities of different solvent extracted samples isolated from different parts of Physalis ixocarpa through disc diffusion assay using three different concentrations. Statistical analysis of the data revealed that different parts of the plant showed varying degree of inhibition against different bacteria at different concentrations. Different solvent extracted samples from the calyx showed inhibitory activity against most of the bacteria under study. Extracts from leaf and fruit samples showed activity against S. aureus and K. pneumoniae and extracts from the stem tissues were effective to control the growth of E. coli and K. pneumoniae. Crude methanolic extract from the stem and n-butanol extracted samples from fruit exhibited strong inhibitory activity against Klebsiella pneumoniae at highest concentrations. Antifungal activity was observed only in crude methanol extract from the leaf against Rhizopus stolinifer, Aspergillus niger and Penicillium chrysogenum.
本研究通过纸片扩散法,使用三种不同浓度,对从酸浆不同部位分离得到的不同溶剂提取物的抗菌活性进行了研究。数据的统计分析表明,该植物的不同部位在不同浓度下对不同细菌表现出不同程度的抑制作用。来自花萼的不同溶剂提取物对大多数受试细菌具有抑制活性。叶和果实样品的提取物对金黄色葡萄球菌和肺炎克雷伯菌有活性,茎组织的提取物对大肠杆菌和肺炎克雷伯菌的生长有抑制作用。茎的粗甲醇提取物和果实的正丁醇提取物在最高浓度下对肺炎克雷伯菌表现出较强的抑制活性。仅在叶的粗甲醇提取物中观察到对匍枝根霉、黑曲霉和产黄青霉的抗真菌活性。