Institut für Organische Chemie, Universität Regensburg, Universitätsstr. 31, 93053 Regensburg, Germany.
Laboratorio de Organocatálisis Asimétrica, Departamento de Química Orgánica, Instituto de Síntesis Química y Catálisis Homogénea (ISQCH), CSIC-Universidad de Zaragoza, Pedro Cerbuna 12, 50009 Zaragoza, Spain.
Soft Matter. 2016 May 11;12(19):4361-74. doi: 10.1039/c5sm02997j.
Chiral N,N'-disubstituted squaramide has been found to undergo self-assembly in a variety of alcoholic solvents at low concentrations leading to the formation of novel nanostructured supramolecular alcogels. The gels responded to thermal, mechanical, optical and chemical stimuli. Solubility studies, gelation ability tests and computer modeling of a series of structurally related squaramides proved the existence of a unique combination of non-covalent molecular interactions and favorable hydrophobic/hydrophilic balance in that drive the anisotropic growth of alcogel networks. The results have also revealed a remarkable effect of ultrasound on both the gelation kinetics and the properties of the alcogels.
手性 N,N'-取代的螺二酰胺在低浓度下于各种醇溶剂中发生自组装，形成新颖的纳米结构超分子醇凝胶。这些凝胶对热、机械、光学和化学刺激有响应。一系列结构相关螺二酰胺的溶解研究、凝胶形成能力测试和计算机建模证明了存在独特的非共价分子相互作用组合和有利的疏水性/亲水性平衡，驱动了醇凝胶网络的各向异性生长。结果还表明超声对手性 N,N'-取代的螺二酰胺在醇凝胶中的凝胶化动力学和性质有显著影响。
