小鼠癌和肉瘤的可治愈性与肿瘤体积之间的关系。
Relation between curability and tumor volume in a murine carcinoma and sarcoma.
作者信息
Shaeffer J, El-Madhi A M, Wakley J
出版信息
Acta Radiol Ther Phys Biol. 1977 Aug;16(4):369-77. doi: 10.3109/02841867709133957.
PMID:270891
Abstract
Tumor control doses (TCD50) using single 60CO doses were determined on C3HBA adenocarcinoma and Dunn osteosaroma ranging in size from microscopic pulmonary colonies (3 X 13(-5) mm3) to palpable subcutaneous tumors (300 mm3) in the hind limb. The power function TCD50 =23.57 TV0.15, with TCD50 in GY and TV (tumor volume) in mm3, fits the data for both tumors over the entire range of tumor volumes used.
摘要
使用单次60钴剂量测定了C3HBA腺癌和邓恩骨肉瘤的肿瘤控制剂量（TCD50），肿瘤大小范围从微小肺集落（3×10⁻⁵立方毫米）到后肢可触及的皮下肿瘤（300立方毫米）。幂函数TCD50 = 23.57TV⁰.¹⁵，其中TCD50以戈瑞为单位，TV（肿瘤体积）以立方毫米为单位，在所用肿瘤体积的整个范围内均符合两种肿瘤的数据。
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