O'Connell M, Cooper S, Perry J C, Hoke L
Department of Psychiatry, Cambridge Hospital, MA 02139.
J Nerv Ment Dis. 1989 May;177(5):273-8. doi: 10.1097/00005053-198905000-00004.
Often patients with personality and affective disorder are troubled by psychotic and psychotic-like symptoms. Predicting a course that includes such symptoms, and subsequently adjusting treatment to take into consideration the added difficulties presented by psychosis, is clinically important. In the current study, a measure of thought disorder, the Thought Disorder Index (TDI), significantly predicted prospective psychotic and psychotic-like symptoms in a sample of 49 personality and affective disorder patients. Multiple regressions demonstrated that the TDI had predictive value above and beyond that of a clinical interview. The high prevalence of psychotic symptoms was most striking in patients with borderline personality disorder.
患有个性与情感障碍的患者常常受到精神病性症状及类精神病性症状的困扰。预测包含此类症状的病程,并随后调整治疗方案以考虑到精神病带来的额外困难,在临床上具有重要意义。在当前研究中,一种思维障碍测量工具——思维障碍指数(TDI),在49名个性与情感障碍患者样本中显著预测了前瞻性精神病性症状及类精神病性症状。多元回归表明,TDI具有超出临床访谈的预测价值。精神病性症状的高患病率在边缘型人格障碍患者中最为显著。