Formisano A, Bammann K, Fraterman A, Hadjigeorgiou C, Herrmann D, Iacoviello L, Marild S, Moreno L A, Nagy P, Van Den Bussche K, Veidebaum T, Lauria F, Siani A
Epidemiology and Population Genetics, Institute of Food Sciences, CNR, Avellino, Italy.
Institute for Public Health and Nursing Science, Bremen University, Bremen, Germany; Leibniz Institute for Prevention Research and Epidemiology BIPS GmbH, Bremen, Germany.
Nutr Metab Cardiovasc Dis. 2016 Jun;26(6):510-6. doi: 10.1016/j.numecd.2016.02.012. Epub 2016 Feb 24.
Several studies demonstrated that larger neck circumference (NC) in children and adolescents may help to identify obesity and cardio-metabolic abnormalities. We aimed to evaluate the correlation between NC and metabolic syndrome (MetS) risk factors and to determine the utility of this anthropometric index to identify MetS in European children.
The present cross-sectional analysis includes 15,673 children (3-10 years) participating in the IDEFICS study. A continuous MetS (cMetS) score was calculated summing age and sex standardized z-scores of specific MetS risk factors. Receiver Operating Characteristic analysis, stratified by one-year age groups, was used to determine the ability of NC to identify children with unfavorable metabolic profile, corresponding to cMetS score ≥ 90th percentile. The areas under the curve values for NC associated with cMetS score values ≥ 90th percentile were significantly greater in girls than in boys (p < 0.001), except for 5 < 6 years group. For boys, optimal NC cut-off values ranged from 26.2 cm for the lowest age group (3 < 4 years), up to 30.9 cm for the highest age group (9 < 10 years). In girls, corresponding values varied from 24.9 cm to 29.6 cm.
The study demonstrated the efficacy of NC in identifying European children with an unfavorable metabolic profile.
多项研究表明，儿童和青少年较大的颈围（NC）可能有助于识别肥胖和心血管代谢异常。我们旨在评估颈围与代谢综合征（MetS）风险因素之间的相关性，并确定该人体测量指标在识别欧洲儿童代谢综合征方面的效用。
本横断面分析纳入了15673名3至10岁参与IDEFICS研究的儿童。通过将特定代谢综合征风险因素的年龄和性别标准化z评分相加来计算连续代谢综合征（cMetS）评分。采用按一岁年龄组分层的受试者工作特征分析，以确定颈围识别代谢状况不佳儿童的能力，即cMetS评分≥第90百分位数。除5至6岁组外，与cMetS评分≥第90百分位数相关的颈围曲线下面积值在女孩中显著大于男孩（p<0.001）。对于男孩，最佳颈围截断值范围从最低年龄组（3至4岁）的26.2厘米到最高年龄组（9至10岁）的30.9厘米。在女孩中，相应的值从24.9厘米到29.6厘米不等。
该研究证明了颈围在识别代谢状况不佳的欧洲儿童方面的有效性。
