Guenifi W, Boukhrissa H, Gasmi A, Rais M, Ouyahia A, Hachani A, Diab N, Mechakra S, Lacheheb A
Service des maladies infectieuses, université Ferhat Abbes Sétif 1, CHU de Sétif, 19000 Sétif, Algérie.
Service des maladies infectieuses, université Ferhat Abbes Sétif 1, CHU de Sétif, 19000 Sétif, Algérie.
J Mal Vasc. 2016 May;41(3):210-4. doi: 10.1016/j.jmv.2016.03.002. Epub 2016 Apr 15.
Cerebral venous thrombosis is a rare disease characterized by its clinical polymorphism and multiplicity of risk factors. Infections represent less than 10% of etiologies. Tuberculosis is not a common etiology, only a few observations are published in the literature. Between January 2005 and March 2015, 61 patients were hospitalized for neuro-meningeal tuberculosis. Among them, three young women had presented one or more cerebral venous sinus thromboses. No clinical feature was observed in these patients; vascular localizations were varied: sagittal sinus (2 cases), lateral sinus (2 cases) and transverse sinus (1 case). With anticoagulant and antituberculosis drugs, the outcome was favorable in all cases. During neuro-meningeal tuberculosis, the existence of consciousness disorders or neurological focal signs is not always the translation of encephalitis, hydrocephalus, tuberculoma or ischemic stroke; cerebral venous sinus thrombosis may be the cause and therefore should be sought.
脑静脉血栓形成是一种罕见疾病,其特点是临床症状多样且危险因素众多。感染在病因中所占比例不到10%。结核病并非常见病因,文献中仅发表了少数病例报道。2005年1月至2015年3月期间,61例患者因神经脑膜结核住院。其中,三名年轻女性出现了一处或多处脑静脉窦血栓形成。这些患者未观察到临床特征;血管定位各不相同:上矢状窦(2例)、外侧窦(2例)和横窦(1例)。使用抗凝药和抗结核药后,所有病例的预后均良好。在神经脑膜结核期间,意识障碍或神经局灶体征的存在并不总是脑炎、脑积水、结核瘤或缺血性中风的表现;脑静脉窦血栓形成可能是病因,因此应予以排查。