Labbad Ibrahim, Hamzeh Ghassan
Faculty of Medicine, Damascus University, Damascus, Syria.
Ann Med Surg (Lond). 2023 Apr 15;85(5):2190-2193. doi: 10.1097/MS9.0000000000000652. eCollection 2023 May.
Cerebral venous thrombosis (CVT) is a relatively common disease. Risk factors for CVT include pregnancy, cancer, autoimmune diseases, and hypercoagulation. Acute and chronic meningitis are also considered predisposing conditions for CVT. Cases of CVT associated with tuberculous meningitis and miliary tuberculosis (TB) are rare in the medical literature, and here the authors report the first case report from Middle East.
The authors present a 33-year-old female patient diagnosed initially with CVT to discover the presence of tuberculous meningitis and miliary TB.
CVT is an urgent condition and the outcome is usually good when treated quickly. The mechanisms of TB causing thrombosis are endothelial injury, slow venous flow, and increased platelet aggregation. The clinical presentation of CVT can be confused and falsely attributed to TB Meningitis.
Infectious causes of CVT should always be remembered, especially TB should be in mind in developing countries.
脑静脉血栓形成(CVT)是一种相对常见的疾病。CVT的危险因素包括妊娠、癌症、自身免疫性疾病和高凝状态。急性和慢性脑膜炎也被认为是CVT的易感因素。在医学文献中,与结核性脑膜炎和粟粒性肺结核(TB)相关的CVT病例很少见,本文作者报告了中东地区的首例病例。
作者介绍了一名33岁女性患者,最初被诊断为CVT,后来发现患有结核性脑膜炎和粟粒性肺结核。
CVT是一种紧急情况,若能迅速治疗,通常预后良好。结核导致血栓形成的机制是内皮损伤、静脉血流缓慢和血小板聚集增加。CVT的临床表现可能会令人困惑,并被错误地归因于结核性脑膜炎。
应始终牢记CVT的感染性病因,在发展中国家尤其应考虑到结核病。