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沿锌路行驶。

Driving Along the Zinc Road.

机构信息

Center for Nutritional Sciences, Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida 32611-2710; email:

出版信息

Annu Rev Nutr. 2016 Jul 17;36:1-15. doi: 10.1146/annurev-nutr-071715-050854. Epub 2016 Apr 18.

Abstract

After having written hundreds of research articles, reviews, and book chapters, I find it awkward to pen an autobiography. I still do use a pen. As stated by others in the nutrition field who have written of their own experiences in a perspective article for the Annual Review of Nutrition, my course through this field of science has been serendipitous. My interest in nutrition developed during my experiences with horses and then Angus cattle and entry into an animal science degree program. As the age of molecular biology was unfolding, I pursued a PhD in nutritional biochemistry with Hamilton Eaton at the University of Connecticut followed by postdoctoral work with Hector DeLuca at the University of Wisconsin, working on vitamins A and D, respectively. At Rutgers University, one of the two institutions where I have served on the faculty, I started my research program on trace elements with a focus on cadmium toxicity but soon thereafter began my research on zinc metabolism and function. I moved to the University of Florida in 1982 for an endowed position and have been a Florida Gator ever since. At the University of Florida, research expanded to include identification of zinc-responsive genes and physiological outcomes of zinc transport influencing health and disease, particularly as related to inflammation. I had the opportunity to contribute national science policy as president of both the Federation of American Societies for Experimental Biology and the American Society for Nutrition. As the time of this writing, I maintain an active laboratory.

摘要

在撰写了数百篇研究文章、评论和书籍章节之后,我发现写自传很尴尬。我仍然使用钢笔。正如其他在营养领域撰写过自己经验的人在《营养年度评论》的一篇观点文章中所指出的那样,我在这个科学领域的历程是偶然的。我对营养的兴趣是在我与马的经历以及后来进入动物科学学位课程的过程中发展起来的。随着分子生物学时代的到来,我在康涅狄格大学的汉密尔顿·伊顿(Hamilton Eaton)攻读营养生物化学博士学位,随后在威斯康星大学的赫克托·德卢卡(Hector DeLuca)从事博士后工作,分别研究维生素 A 和维生素 D。在罗格斯大学,这是我在两个教职机构中的一个,我开始了我的微量元素研究计划,重点是研究镉毒性,但不久之后,我开始了锌代谢和功能的研究。1982 年,我搬到佛罗里达大学担任特聘教授,从那以后一直是佛罗里达大学的一员。在佛罗里达大学,研究扩展到包括鉴定锌反应基因和锌转运对健康和疾病的生理影响,特别是与炎症有关的影响。我有机会作为美国实验生物学联合会和美国营养学会的主席为国家科学政策做出贡献。在撰写本文时,我仍保持着活跃的实验室。

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