Dedeoglu Reyhan, Bilici Meki, Demir Fikri, Demir Fadli, Acar Onur Çağlar, Hallioglu Olgu, Pac Ayşenur, Kiziltas Alev, Karabel Duran, Kula Serdar, Cimen Derya, Baspinar Osman, Atik Sezen Ugan, Saltik Irfan Levent
Cerrahpasa Medical Faculty, Department of Pediatric Cardiology, İstanbul University, Istanbul, Turkey.
Medical Faculty, Department of Pediatric Cardiology, Dicle University, Diyarbakır, Turkey.
J Interv Cardiol. 2016 Jun;29(3):325-31. doi: 10.1111/joic.12290. Epub 2016 Apr 19.
Over the past 2 decades, transcatheter occlusion of patent ductus arteriosus (PDA) with coils and the duct occluders evolved to be the procedure of choice. A new device, the Occlutech PDA® occluder (ODO) device has been designed. Herein, we aimed to evaluate the characteristics and short-term results of patients who underwent transcatheter closure of PDA using the ODO.
We reviewed the clinical records of 60 patients from different centers in Turkey between December 2013 and January 2016. The medical records were reviewed for demographic characteristics and echocardiographic findings. Device size was selected on the narrowest diameter of PDA.
The median patient age was 2.5 years (6 months-35 years), and median PDA diameter was 2.5 mm (1.2-11 mm). Fifty-eight of 60 patients (96.6%) had successful ODO implantation. The occlusion rates were 37/58 (63.7%) at the end of the procedure, 51/58 (87.9%) at 24-48 hours post-procedure, and 57/58 (98.2%) on echocardiography at a median follow-up of 7.6 months.
Our results indicate that transcatheter closure of PDA using the ODO is effective. Larger studies and longer follow-up are required to assess whether its shape and longer length make it superior to other duct occluders in large, tubular, or window-type ducts. (J Interven Cardiol 2016;29:325-331).
在过去20年中，经导管使用弹簧圈和动脉导管封堵器封堵动脉导管未闭（PDA）已成为首选治疗方法。一种新型装置，即Occlutech PDA®封堵器（ODO）已被设计出来。在此，我们旨在评估使用ODO经导管封堵PDA患者的特征和短期结果。
我们回顾了2013年12月至2016年1月期间来自土耳其不同中心的60例患者的临床记录。对病历进行人口统计学特征和超声心动图检查结果的回顾。根据PDA最窄直径选择装置尺寸。
患者年龄中位数为2.5岁（6个月至35岁），PDA直径中位数为2.5毫米（1.2至11毫米）。60例患者中有58例（96.6%）成功植入ODO。手术结束时封堵率为37/58（63.7%），术后24至48小时为51/58（87.9%），在中位随访7.6个月时超声心动图显示封堵率为57/58（98.2%）。
我们的结果表明，使用ODO经导管封堵PDA是有效的。需要进行更大规模的研究和更长时间的随访，以评估其形状和更长的长度是否使其在大型、管状或窗型导管中优于其他动脉导管封堵器。（《介入心脏病学杂志》2016年；29：325 - 331）
