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双边结直肠癌审计中结直肠手术死亡率分析

Analysis of mortality in colorectal surgery in the Bi-National Colorectal Cancer Audit.

作者信息

Teloken Patrick Ely, Spilsbury Katrina, Platell Cameron

机构信息

Colorectal Surgical Unit, St John of God Subiaco Hospital, University of Western Australia, Perth, Western Australia, Australia.

出版信息

ANZ J Surg. 2016 Jun;86(6):454-8. doi: 10.1111/ans.13523. Epub 2016 Apr 18.

Abstract

BACKGROUND

In the last decade, there has been a significant increase in interest for public reporting of outcome data and performance comparison across institutions and surgeons. This study aims at comparing postoperative mortality after colorectal cancer surgery across units and individual consultants in Australia and New Zealand using funnel plots.

METHODS

The Bi-National Colorectal Cancer Audit database was used. Unadjusted and adjusted funnel plots of inpatient mortality were constructed. Risk adjustment was based upon multivariable logistic regression models using purposeful covariate selection.

RESULTS

A total of 10 008 patients undergoing surgery for colorectal cancer from 56 surgical units and 90 consultants were identified. Overall inpatient mortality was 1.51%, corresponding to 1.1% for elective and 3.9% for urgent cases. Logistic regression identified age, American Society of Anesthesiologists score, urgent surgery and open surgery to be independently associated with inpatient mortality. Unadjusted and adjusted funnel plot analysis identified three (5.3%) units exceeding the inner limit and none exceeding the outer limit. Six (6.6%) consultants had inpatient mortality between the upper inner and outer limits and one (1.1%) between the inferior inner and outer limits. Upon adjustment, seven (7.7%) consultants had inpatient mortality between the inner and outer limit. Potential limitations of this study include: residual confounding being responsible for the association of open surgery and mortality; incomplete case-mix adjustment resulting in outlier identification; and bias towards inclusion of larger institutions.

CONCLUSION

Mortality figures in Australia and New Zealand are comparable to recently reported international data. The vast majority of units and consultants are performing within the expected boundaries.

摘要

背景

在过去十年中,人们对公开报告结果数据以及跨机构和外科医生进行绩效比较的兴趣显著增加。本研究旨在使用漏斗图比较澳大利亚和新西兰各单位及个体顾问医生进行结直肠癌手术后的术后死亡率。

方法

使用双边结直肠癌审计数据库。构建了未调整和调整后的住院死亡率漏斗图。风险调整基于使用有目的协变量选择的多变量逻辑回归模型。

结果

共识别出来自56个手术单位和90名顾问医生的10008例接受结直肠癌手术的患者。总体住院死亡率为1.51%,择期手术为1.1%,急诊手术为3.9%。逻辑回归确定年龄、美国麻醉医师协会评分、急诊手术和开放手术与住院死亡率独立相关。未调整和调整后的漏斗图分析确定有3个(5.3%)单位超过了内限,没有单位超过外限。6名(6.6%)顾问医生的住院死亡率处于上内限和外限之间,1名(1.1%)处于下内限和外限之间。调整后,7名(7.7%)顾问医生的住院死亡率处于内限和外限之间。本研究的潜在局限性包括:开放手术与死亡率之间的关联可能存在残余混杂因素;病例组合调整不完整导致异常值识别;以及倾向于纳入较大机构。

结论

澳大利亚和新西兰的死亡率数据与最近报告的国际数据相当。绝大多数单位和顾问医生的表现都在预期范围内。

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