Kogawa Rikitake, Watanabe Ichiro, Okumura Yasuo, Mano Hiroaki, Sonoda Kazumasa, Nagashima Koichi, Sasaki Naoko, Ohkubo Kimie, Takahashi Keiko, Iso Kazuki, Kurokawa Sayaka, Nakai Toshiko, Hirayama Atsushi
Division of Cardiology, Department of Medicine, Nihon University School of Medicine, 30-1 Oyaguchi-kami, Itabashi-ku, Tokyo 173-8610, Japan.
J Arrhythm. 2016 Apr;32(2):108-11. doi: 10.1016/j.joa.2015.10.001. Epub 2015 Nov 27.
Although alteration of the amplitude and morphology of bipolar electrograms is used widely as a guide of the ablation effect, there is little information concerning unipolar electrograms. The amplitude and morphology of filtered bipolar (BP) and filtered unipolar (UP) electrograms were compared during pulmonary vein isolation in patients with atrial fibrillation.
BP (30-250 Hz) and UP (30-100 Hz) signals from the ablation catheter were recorded before and after each ablation point at the pulmonary vein antrum in 6 patients with atrial fibrillation.
In the electrogram group with low-voltage amplitude in BP electrograms before ablation (<0.5 mV), the reduction in amplitude after ablation was significantly greater in the UP than in the BP electrograms, whereas the reduction was similar between the two recording methods in the electrogram group with high-voltage amplitude in BP electrograms (≥0.5 mV). Furthermore, the S wave in the UP electrograms disappeared at the sites of no pace capture after ablation, whereas no characteristic morphologic changes were observed in the BP electrograms.
Filtered UP electrograms may be useful in assessing the effectiveness of lesion formation.
尽管双极电图的振幅和形态改变被广泛用作消融效果的指导，但关于单极电图的信息却很少。在心房颤动患者的肺静脉隔离过程中，对滤波后的双极（BP）和滤波后的单极（UP）电图的振幅和形态进行了比较。
记录6例心房颤动患者在肺静脉窦每个消融点前后消融导管的BP（30 - 250Hz）和UP（30 - 100Hz）信号。
在消融前BP电图电压振幅低（<0.5mV）的电图组中，消融后UP电图的振幅降低明显大于BP电图，而在BP电图电压振幅高（≥0.5mV）的电图组中，两种记录方法的降低幅度相似。此外，消融后无夺获部位的UP电图中的S波消失，而BP电图未观察到特征性形态学改变。
滤波后的UP电图可能有助于评估损伤形成的有效性。
