Morales L, Rovira J, Rottermann M, Juliá V
Department of Pediatrics, Hospital Clinico y Provincial, University of Barcelona, Spain.
J Pediatr Surg. 1989 Mar;24(3):276-81. doi: 10.1016/s0022-3468(89)80012-0.
In the last 10 years, four children with adrenocortical tumors were treated in our hospital. Three of them had symptoms of adrenogenital virilizing syndrome, and another, nonfunctional, was found during a routine examination. A diagnosis of adrenocortical tumor was established given the symptoms, hormonal tests, and radiologic studies. Two of the tumors were located in the left side, and the histologic diagnosis was pleomorphic cortical adenoma; the ones that affected the right side were adenocarcinomas. All the patients were treated by surgery and none received chemotherapy. At both presurgical and postsurgical stages, the patients were treated with cortisol. All four children have had a favorable course, with normal growth and the disappearance of public hair and hirsutism; however, macrogenitals still persist.
在过去10年里，我院共治疗了4例肾上腺皮质肿瘤患儿。其中3例有肾上腺性征异常综合征的症状，另一例无功能肿瘤是在常规检查中发现的。根据症状、激素检测和影像学检查确诊为肾上腺皮质肿瘤。2例肿瘤位于左侧，组织学诊断为多形性皮质腺瘤；右侧的为腺癌。所有患者均接受了手术治疗，无一例接受化疗。在手术前后阶段，患者均接受了皮质醇治疗。所有4名患儿病情转归良好，生长正常，阴毛和多毛症消失；然而，巨生殖器仍然存在。
