Fraga Thiago Leite, Fernandes Magda Freitas, Pontes Elenir Rose Jardim Cury, Levay Ana Paula Silva, Almeida da Cunha Elenice Brandão, França Adriana de Oliveira, Dorval Maria Elizabeth Cavalheiros
From the *Universidade Federal do Mato Grosso do Sul (UFMS), Programa de Pós-graduação em Doenças Infecciosas e Parasitárias, Laboratório de Parasitologia Clínica, Campo Grande, and †Universidade Federal da Grande Dourados (UFGD), Laboratório de Entomologia, Dourados, Mato Grosso do Sul, Brasil.
Pediatr Infect Dis J. 2016 Jul;35(7):805-7. doi: 10.1097/INF.0000000000001172.
The aim of the present study was to assess the presence of antissaliva antibodies of Lutzomyia longipalpis in human hosts living in area of visceral leishmaniasis, located in the Center-West region of Brazil. The presence of antissaliva antibodies of L. longipalpis exhibited a strong correlation with the protection and development of antibodies against Leishmania sp. Of the 492 children studied, elevated antissaliva antibodies of L. longipalpis were detected in 38.4% of the participants. There was a higher percentage of positivity (64.7%) among children who exhibited anti-Leishmania sp. antibodies and among those who were positive in the delayed hypersensitivity test (34.8%).
本研究的目的是评估生活在巴西中西部地区内脏利什曼病流行区的人类宿主中长须罗蛉抗唾液抗体的存在情况。长须罗蛉抗唾液抗体的存在与抗利什曼原虫属抗体的产生及保护作用密切相关。在492名研究儿童中，38.4%的参与者检测到长须罗蛉抗唾液抗体水平升高。在出现抗利什曼原虫属抗体的儿童以及迟发型超敏反应试验呈阳性的儿童中（34.8%），阳性率更高（64.7%）。
