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针对食管静脉曲张进行门体分流术的二十五年

A quarter of a century of portasystemic shunting for oesophageal varices.

作者信息

Deans G T, Spence R A, Johnston G W

出版信息

J R Coll Surg Edinb. 1989 Feb;34(1):37-9.

PMID:2709357
Abstract

Seventy-three patients who had received portasystemic shunts were reviewed to assess the current role of this procedure in the treatment of portal hypertension. Survival at 1, 5 and 10 years was 85%, 68% and 45% respectively. Survival was significantly greater (P less than 0.001) in Child's grade A patients compared with Child's grade B patients and in non-alcoholics compared with alcoholics. Previously absent encephalopathy developed in 43% of those with non-selective shunts compared with 21% of those with selective shunts. Six of the 12 patients who experienced recurrent variceal haemorrhage had associated shunt thrombosis: five of these required further shunts or oesophageal transection to control their bleeding and the other patient died before further surgery could be instituted. Shunt surgery still has a role in the treatment of a small number of carefully selected patients with portal hypertension.

摘要

对73例接受门体分流术的患者进行了回顾性研究,以评估该手术在门静脉高压治疗中的当前作用。1年、5年和10年生存率分别为85%、68%和45%。与Child B级患者相比,Child A级患者的生存率显著更高(P<0.001);与酒精性肝病患者相比,非酒精性肝病患者的生存率显著更高。43%的非选择性分流患者出现了先前未有的肝性脑病,而选择性分流患者的这一比例为21%。12例复发性静脉曲张出血患者中有6例伴有分流血栓形成:其中5例需要进一步分流或食管横断术来控制出血,另1例患者在能够进行进一步手术之前死亡。分流手术在少数经过精心挑选的门静脉高压患者的治疗中仍具有一定作用。

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