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探索低出生体重的持续黑箱风险:全球低出生体重研究(GLOWBS Study)的发现

Exploring the persistent black risk of low birthweight: findings from the GLOWBS Study.

作者信息

Levin J S, Markides K S, Richardson J C, Lubin A H

出版信息

J Natl Med Assoc. 1989 Mar;81(3):253-60.

Abstract

Results are presented from the Galveston Low Birthweight Survey (GLOWBS) Study, a tri-ethnic survey (N = 1,179) of live, single births, conducted in Galveston, Texas, from 1986 to 1987. Four principal findings emerged pointing to a persistent black risk for low birthweight (less than 2,500g). First, black infants (2,997g) have significantly lower mean birthweight than either Anglos (3,281g) or Hispanics (3,270g). Second, blacks are at significantly higher risk of low birthweight than nonblacks (risk ratio = 1.71). Third, despite controlling for a variety of pregnancy- and health-related, psychosocial, socioeconomic, and health services factors (including even gestational length), being black still exerts a significant, inverse effect on birthweight (beta = -0.137). Fourth, of the above factors only gestational length (R2 = 0.39) accounts for more than a negligible amount of the total variance in birthweight among blacks. These findings are discussed, and several lines of follow-up research are proposed.

摘要

本文展示了加尔维斯顿低体重儿调查(GLOWBS)的研究结果。该研究是一项针对德克萨斯州加尔维斯顿市1986年至1987年期间单胎活产的三族裔调查(N = 1,179)。研究得出了四项主要发现,表明黑人低体重儿(体重低于2500克)的风险持续存在。首先,黑人婴儿(平均体重2997克)的平均出生体重显著低于盎格鲁人(3281克)或西班牙裔(3270克)。其次,黑人出现低体重儿的风险显著高于非黑人(风险比 = 1.71)。第三,尽管对各种与妊娠、健康、心理社会、社会经济和医疗服务相关的因素进行了控制(甚至包括孕周),但黑人身份仍对出生体重产生显著的反向影响(β = -0.137)。第四,在上述因素中,只有孕周(R2 = 0.39)对黑人出生体重总方差的解释量超过了可忽略不计的程度。本文对这些发现进行了讨论,并提出了几条后续研究方向。

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