Ghosh Sudip K, Roy Sanjoy, Chekan Ed, Fegelman Elliott J
Global Health Economics and Market Access, Ethicon Inc., 4545 Creek Road ML 96, Cincinnati, OH, USA.
Medical Affairs, Ethicon Inc., Cincinnati, OH, USA.
Obes Surg. 2016 Jul;26(7):1601-6. doi: 10.1007/s11695-016-2177-1.
The primary objective of this review was to assess the incidence of intraoperative staple line leaks and bleeds during laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB). A literature search of MEDLINE®, EMBASE™, and Biosis from January 2010 to November 2014, plus secondary citations extending to 2008, identified 16 relevant articles. For LSG, the incidence of intraoperative leaks and bleeds was as high as 3.93 and 4.07 %, respectively. For LRYGB, leaks occurred in up to 8.26 % and bleeds in 3.45 % of cases. Stapler misfire was commonly cited as a cause. Widespread, precautionary use of staple line reinforcement (SLR), lack of standardized testing, and underreporting suggest the incidence may be underestimated. Published studies were insufficient to address the economic impact of bleeds and leaks or interventions, but development of improved stapler designs that obviate the need for SLR may reduce costs and improve outcomes.
本综述的主要目的是评估腹腔镜袖状胃切除术(LSG)和腹腔镜Roux-en-Y胃旁路术(LRYGB)术中吻合钉线渗漏和出血的发生率。对2010年1月至2014年11月期间的MEDLINE®、EMBASE™和Biosis进行文献检索,并补充截至2008年的二次引用文献,共识别出16篇相关文章。对于LSG,术中渗漏和出血的发生率分别高达3.93%和4.07%。对于LRYGB,高达8.26%的病例发生渗漏,3.45%的病例发生出血。吻合器故障常被认为是原因。广泛预防性使用吻合钉线加固(SLR)、缺乏标准化检测以及报告不足表明发生率可能被低估。已发表的研究不足以探讨出血和渗漏或干预措施的经济影响,但开发无需SLR的改良吻合器设计可能会降低成本并改善结果。