Rowe James R, Biggerstaff Kyle D, Ben-Ezra Vic, Nichols David L, DiMarco Nancy
Int J Sport Nutr Exerc Metab. 2016 Oct;26(5):435-444. doi: 10.1123/ijsnem.2015-0274. Epub 2016 Aug 24.
This study examined the effect of prior exercise on postprandial lipemia (PPL) concentration following a mixed meal (MM) made with either glucose or fructose. Sedentary women completed four trials in random order: 1) Rest-Fructose: RF, 2) Rest-Glucose: RG, 3) Exercise-Fructose: EF, 4) Exercise-Glucose: EG. Exercise expended 500 kcal while walking at 70%VO. Rest was 60 min of sitting. The morning after each trial, a fasting (12 hr) blood sample was collected followed by consumption of the MM. The MM was blended with whole milk and ice cream plus a glucose or fructose powder. Glucose and fructose powder accounted for 30% of the total kcal within the MM. Blood was collected periodically for 6 hr post-MM and analyzed for PPL. Magnitude of PPL over the 6 hr postmeal was quantified using the triglyceride incremental area under the curve (TG AUC). Significant differences (p < .05) between trials were determined using repeated-measures ANOVA and Bonferroni post hoc test. There was no significant difference in the TG AUC between the four trials (p > .05). A significant trial by time interaction for TG concentration was reported (p < .05). Despite lack of change in the AUC with prior exercise, the lower TG concentration at multiple time points in the EG trial does indicate that prior exercise has some desirable effect on PPL. This study suggests that replacing fructose with glucose sugars and incorporating exercise may minimize PPL following a mixed meal but exercise will need to elicit greater energy expenditure.
本研究考察了预先进行运动对食用含葡萄糖或果糖的混合餐（MM）后餐后血脂（PPL）浓度的影响。久坐不动的女性按随机顺序完成四项试验：1）休息-果糖：RF，2）休息-葡萄糖：RG，3）运动-果糖：EF，4）运动-葡萄糖：EG。运动在以70%VO₂的强度步行时消耗500千卡热量。休息为静坐60分钟。每次试验后的早晨，采集空腹（12小时）血样，随后食用混合餐。混合餐由全脂牛奶、冰淇淋加葡萄糖或果糖粉混合而成。葡萄糖和果糖粉占混合餐总热量的30%。混合餐后6小时定期采集血液并分析餐后血脂。使用曲线下甘油三酯增量面积（TG AUC）对餐后6小时内餐后血脂的幅度进行量化。使用重复测量方差分析和Bonferroni事后检验确定试验之间的显著差异（p < 0.05）。四项试验之间的TG AUC无显著差异（p > 0.05）。报告了TG浓度随时间的显著试验交互作用（p < 0.05）。尽管预先运动后AUC没有变化，但EG试验中多个时间点较低的TG浓度确实表明预先运动对餐后血脂有一些有益影响。本研究表明，用葡萄糖替代果糖并进行运动可能会使混合餐后的餐后血脂降至最低，但运动需要消耗更多能量。
