一名11岁女孩的异位甲状旁腺腺瘤：病例报告及文献综述
Ectopic Parathyroid Adenoma in an 11-Year-Old Girl: Case Report and Literature Review.
作者信息
Flokas Myrto Eleni, Ganieva Gulnigor, Grieco Amanda, Agdere Levon
机构信息
Division of Pediatric Endocrinology, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, New York.
Division of Pediatric Endocrinology, Joe DiMaggio Children's Hospital, Hollywood, Florida.
出版信息
AACE Clin Case Rep. 2020 Nov 28;7(1):51-56. doi: 10.1016/j.aace.2020.11.013. eCollection 2021 Jan-Feb.
OBJECTIVE
Primary hyperparathyroidism secondary to an ectopic parathyroid adenoma is rare among children and adolescents.
METHODS
We describe the case of an 11-year-old girl with incidentally diagnosed primary hyperparathyroidism secondary to an intrathymic parathyroid adenoma and performed a review of the related literature.
RESULTS
Technetium sestamibi single-photon emission computerized tomography/computed tomography and 4-dimensional computed tomography confirmed the ectopic location of the adenoma. The patient underwent thoracoscopic thymectomy and remained normocalcemic with elevated parathyroid hormone showing a downward trend. Parathyroid hormone normalized 18 months after successful parathyroidectomy.
CONCLUSION
We review the case of a rare mediastinal parathyroid adenoma in a pediatric patient and summarize the epidemiologic profile, diagnosis, and management of similar pediatric cases.
目的
继发于异位甲状旁腺腺瘤的原发性甲状旁腺功能亢进在儿童和青少年中较为罕见。
方法
我们描述了一名11岁女孩的病例，该女孩偶然诊断为继发于胸腺内甲状旁腺腺瘤的原发性甲状旁腺功能亢进，并对相关文献进行了综述。
结果
锝-99m甲氧基异丁基异腈单光子发射计算机断层扫描/计算机断层扫描和四维计算机断层扫描证实了腺瘤的异位位置。患者接受了胸腔镜胸腺切除术，术后血钙正常，甲状旁腺激素升高呈下降趋势。甲状旁腺激素在成功进行甲状旁腺切除术后18个月恢复正常。
结论
我们回顾了一例儿科患者罕见的纵隔甲状旁腺腺瘤病例，并总结了类似儿科病例的流行病学特征、诊断和治疗方法。
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