Wang Nian-Rong, Ye Ya
Department of Child Health Care, Chongqing Maternal and Child Health Care Hospital, Chongqing 400013, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2016 Apr;18(4):350-4. doi: 10.7499/j.issn.1008-8830.2016.04.014.
To investigate the development of nocturnal sleep pattern in infants.
Fifty healthy full-term newborns born in Chongqing Maternal and Child Health Care Hospital were chosen for a prospective longitudinal study. A non-invasive sleep monitor, Actiwatch, was used to monitor infants' 12 sleep parameters on the 10th day, 28th day, the first Tuesday at the 2nd, 3rd, 4th, 5th, 6th, 9th and 12th month after birth, each monitoring time lasting 60 hours. All sleep parameters were analyzed by two-level mixed effect model.
Twenty-two boys and 25 girls completed the whole follow-up study. From birth to the 12th month after birth, the nocturnal sleep onset latency (NSOL) decreased by about 48% at 3 months of age and by 83% at 6 months of age. The nocturnal sleep efficiency (NSE%) increased from 66% to 87%, the nocturnal total sleep time (NTST) increased from 416 minutes to 517 minutes, and the longest nocturnal continuous sleeping time (L-NCST) increased from 197 minutes to 327 minutes. NSE%, NTST and L-NCST increased with age (P<0.01). The 3rd to 12th month ratios of NSE%, NTST and L-NCST were 86%, 84% and 72%, respectively, and the 6th to 12th month ratios of those were 97%, 91% and 94%, respectively. The nocturnal total wake time (NTWT) and longest nocturnal continuous waking times (L-NCWT) decreased with age (P<0.01). The decline speeds in the first half year were 5-6 times of those in the second half year after birth (P<0.05). NTST, nocturnal continuous sleeping ability and NSE% in boys were lower than those in girls (P<0.05).
Infantile nocturnal sleep patterns develop rapidly during the first 6 months, especially within the first 3 months after birth. Partial infantile sleep parameters are related to gender.
探讨婴儿夜间睡眠模式的发展情况。
选取在重庆妇幼保健院出生的50名健康足月儿进行前瞻性纵向研究。使用无创睡眠监测仪Actiwatch，在出生后第10天、第28天、第2、3、4、5、6、9和12个月的第一个周二监测婴儿的12项睡眠参数，每次监测持续60小时。所有睡眠参数采用两级混合效应模型进行分析。
22名男孩和25名女孩完成了整个随访研究。从出生到出生后12个月，夜间睡眠起始潜伏期（NSOL）在3个月龄时下降约48%，在6个月龄时下降83%。夜间睡眠效率（NSE%）从66%提高到87%，夜间总睡眠时间（NTST）从416分钟增加到517分钟，最长夜间连续睡眠时间（L-NCST）从197分钟增加到327分钟。NSE%、NTST和L-NCST随年龄增长而增加（P<0.01）。NSE%、NTST和L-NCST在第3至12个月的比值分别为86%、84%和72%，在第6至12个月的比值分别为97%、91%和94%。夜间总觉醒时间（NTWT）和最长夜间连续觉醒时间（L-NCWT）随年龄增长而减少（P<0.01）。出生后上半年的下降速度是下半年的5至6倍（P<0.05）。男孩的NTST、夜间连续睡眠能力和NSE%低于女孩（P<0.05）。
婴儿夜间睡眠模式在出生后的前6个月，尤其是出生后的前3个月发展迅速。部分婴儿睡眠参数与性别有关。
