Kitterick Pádraig T, Lucas Laura
a National Institute for Health Research Nottingham Hearing Biomedical Research Unit , 113 The Ropewalk, Nottingham NG1 5DU , UK.
b Otology and Hearing Group, Division of Clinical Neuroscience, School of Medicine , University of Nottingham , UK.
Cochlear Implants Int. 2016 Apr;17 Suppl 1:51-4. doi: 10.1080/14670100.2016.1155806.
Unilateral deafness and highly asymmetric hearing loss can impair listening abilities in everyday situations, create substantial audiological handicap, and reduce overall quality of life. Preliminary evidence suggests that cochlear implantation may be effective in reversing some of these detrimental effects. Patient-level data from existing studies were re-analysed to explore potential factors that may be predictive of improved speech perception scores following implantation.
Logistic regression modelling examined whether improved speech perception following implantation under various listening conditions was related to the duration of deafness of the severe-to-profoundly deaf ear and/or the level of hearing in the better ear.
Patients with a shorter duration of deafness were more likely to improve in listening conditions that created a less favourable SNR at the implanted ear than the non-implanted ear. Those with more residual hearing in the better ear were more likely to improve in the listening condition that created a less favourable SNR at that ear.
The analysis suggests that characteristics of both ears may be relevant when seeking to identify those candidates who are likely to obtain benefit to speech perception following cochlear implantation.
单侧耳聋和高度不对称听力损失会损害日常听力，造成严重的听力学障碍，并降低整体生活质量。初步证据表明，人工耳蜗植入可能有效逆转其中一些有害影响。对现有研究的患者层面数据进行重新分析，以探索可能预测植入后言语感知分数改善的潜在因素。
逻辑回归模型分析了在各种听力条件下，植入后言语感知的改善是否与重度至极重度聋耳的耳聋持续时间和/或较好耳的听力水平有关。
在植入耳信噪比低于未植入耳的听力条件下，耳聋持续时间较短的患者更有可能改善。在该耳信噪比较低的听力条件下，较好耳残余听力较多的患者更有可能改善。
分析表明，在试图确定哪些人工耳蜗植入候选人可能从言语感知改善中获益时，双耳的特征可能都与之相关。
