Chaku Meenakshi, Netland Peter A, Ishida Kyoko, Rhee Douglas J
Department of Ophthalmology, Loyola University Chicago, Maywood, IL, USA.
Department of Ophthalmology, University of Virginia School of Medicine, Charlottesville, VA, USA.
Clin Ophthalmol. 2016 Mar 30;10:547-53. doi: 10.2147/OPTH.S104029. eCollection 2016.
The purpose of this study was to evaluate the risk factors for tube exposure after glaucoma drainage implant surgery.
This was a retrospective case-controlled observational study of 64 eyes from 64 patients. Thirty-two eyes of 32 patients with tube erosion requiring surgical revision were compared with 32 matched control eyes of 32 patients. Univariate and multivariate risk factor analyses were performed.
Mean age was significantly younger in the tube exposure group compared with the control group (48.2±28.1 years versus 67.3±18.0 years, respectively; P=0.003). The proportion of diabetic patients (12.5%) in the tube exposure group was significantly less (P=0.041) compared with the control group (37.5%). Comparisons of the type and position of the drainage implant were not significantly different between the two groups. The average time to tube exposure was 17.2±18.0 months after implantation of the drainage device. In both univariate and multivariate analyses, younger age (P=0.005 and P=0.027) and inflammation prior to tube exposure (P≤0.001 and P=0.004) were significant risk factors. Diabetes was a significant risk factor only in the univariate analysis (P=0.027).
Younger age and inflammation were significant risk factors for tube exposure after drainage implant surgery.
本研究旨在评估青光眼引流植入物手术后引流管暴露的危险因素。
这是一项对64例患者的64只眼进行的回顾性病例对照观察研究。将32例需要手术修复引流管侵蚀的患者的32只眼与32例匹配对照患者的32只眼进行比较。进行了单因素和多因素危险因素分析。
引流管暴露组的平均年龄显著低于对照组(分别为48.2±28.1岁和67.3±18.0岁;P=0.003)。引流管暴露组糖尿病患者的比例(12.5%)显著低于对照组(37.5%,P=0.041)。两组之间引流植入物的类型和位置比较无显著差异。引流装置植入后至引流管暴露的平均时间为17.2±18.0个月。在单因素和多因素分析中,年龄较小(P=0.005和P=0.027)以及引流管暴露前的炎症(P≤0.001和P=0.004)均为显著危险因素。糖尿病仅在单因素分析中为显著危险因素(P=0.027)。
年龄较小和炎症是引流植入物手术后引流管暴露的显著危险因素。