Frings Andreas, Richard Gisbert, Steinberg Johannes, Druchkiv Vasyl, Linke Stephan Johannes, Katz Toam
Department of Ophthalmology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Department of Ophthalmology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany; Ophthalmologikum an der Alster, Hamburg, Germany.
Clin Ophthalmol. 2016 Mar 31;10:565-70. doi: 10.2147/OPTH.S99098. eCollection 2016.
To analyze the refractive and keratometric stability in hyperopic astigmatic laser in situ keratomileusis (LASIK) or photorefractive keratectomy (PRK) during the first 6 months after surgery.
This retrospective cross-sectional study included 97 hyperopic eyes; 55 were treated with LASIK and 42 with PRK. Excimer ablation for all eyes was performed using the ALLEGRETTO excimer laser platform using a mitomycin C for PRK and a mechanical microkeratome for LASIK. Keratometric and refractive data were analyzed during three consecutive follow-up intervals (6 weeks, 3 months, and 6 months). The corneal topography was obtained using Scheimpflug topography, and subjective refractions were acquired by expert optometrists according to a standardized protocol.
After 3 months, mean keratometry and spherical equivalent were stable after LASIK, whereas PRK-treated eyes presented statistically significant (P<0.001) regression of hyperopia. In eleven cases, hyperopic regression of >1 D occurred. The optical zone diameter did not correlate with the development of regression.
After corneal laser refractive surgery, keratometric changes are followed by refractive changes and they occur up to 6 months after LASIK and for at least 6 months after PRK, and therefore, caution should be applied when retreatment is planned during the 1st year after surgery because hyperopic refractive regression can lead to suboptimal visual outcome. Keratometric and refractive stability is earlier achieved after LASIK, and therefore, retreatment may be independent of late regression.
分析远视散光患者接受准分子原位角膜磨镶术(LASIK)或准分子激光角膜切削术(PRK)后6个月内的屈光和角膜曲率稳定性。
这项回顾性横断面研究纳入了97只远视眼;其中55只接受了LASIK治疗,42只接受了PRK治疗。所有眼睛均使用鹰视准分子激光平台进行准分子消融,PRK使用丝裂霉素C,LASIK使用机械微型角膜刀。在连续三个随访期(6周、3个月和6个月)分析角膜曲率和屈光数据。使用眼前节分析系统获取角膜地形图,并由专业验光师按照标准化方案进行主观验光。
3个月后,LASIK术后平均角膜曲率和等效球镜度稳定,而PRK治疗的眼睛远视度数出现了具有统计学意义(P<0.001)的回退。11例患者远视回退超过1 D。光学区直径与回退的发生无关。
角膜激光屈光手术后,角膜曲率变化之后会出现屈光变化,这种变化在LASIK术后持续6个月,在PRK术后至少持续6个月,因此,在术后第1年计划再次治疗时应谨慎,因为远视屈光回退可能导致视觉效果不理想。LASIK术后角膜曲率和屈光稳定性更早实现,因此,再次治疗可能与后期回退无关。