Andreev V G, Filippov K G, Tsypliakovskaia L M, Sergeeva T N
Med Radiol (Mosk). 1989 Apr;34(4):42-6.
The paper is concerned with comparative evaluation of the influence of some therapeutic methods, based on the use of different radiation sources, dose fractionation regimens and radiomodifiers, on thyroid function in laryngeal cancer patients. Thyroid function was retrospectively assessed with regard to a course of disease within 2 yrs. after a radical course of radiation or combined therapy. Concomitant gamma-neutron therapy and radiotherapy in combined radiomodification were shown to produce the most inhibitory effect. Irrespective of a course of disease after a therapeutic course thyroid function in laryngeal cancer patients is decreased within 2 yrs. of observation.
本文关注基于不同辐射源、剂量分割方案和放射增敏剂使用的一些治疗方法对喉癌患者甲状腺功能影响的比较评估。在根治性放疗或综合治疗后的2年内，对甲状腺功能进行了回顾性评估，评估范围涵盖疾病进程。结果显示，在联合放射增敏治疗中，同步伽马-中子治疗和放射治疗产生的抑制作用最大。无论治疗疗程后的疾病进程如何，喉癌患者在观察的2年内甲状腺功能都会下降。
