Oishi K, Okada K, Yoshida O, Yamabe H, Ohno Y, Hayes R B, Schroeder F H
Department of Urology, Faculty of Medicine, Kyoto University, Japan.
Prostate. 1989;14(2):117-22. doi: 10.1002/pros.2990140205.
Demographic risk factors for prostatic cancer were examined in a case-control study of 100 triplets of prostatic cancer patients and age-, hospital-, and admission date-matched control series of benign prostatic hyperplasia (BPH) patients and general hospital patients. A higher risk of prostatic cancer was associated with the following factors: 1) long-term occupation in transport or communication (relative risk [RR] = 4.92, 95% confidence interval [CI]: 1.18-20.5) as compared with hospital controls; 2) the wife having a lower educational level (RR = 1.88, 95%CI: 1.02-3.45) as compared with hospital controls; 3) no past episode of hypertension as compared with BPH controls (RR = 2.30, 95%CI: 1.27-4.15); 4) having several sisters (more than four) as compared with both BPH and hospital controls (RR = 3.82, 95%CI: 1.35-10.8 and RR = 2.94, 95%CI: 1.08-8.03 respectively); 5) dense body hair as compared with hospital controls (RR = 4.28, 95%CI: 1.19-15.4). No significant links were found with blood type, daily drug use, head hair, skin color, body type, smoking habits, religion, body weight, and mental characteristics.
在一项病例对照研究中,对100组前列腺癌患者三胞胎以及年龄、医院和入院日期匹配的良性前列腺增生(BPH)患者和综合医院患者对照组,研究了前列腺癌的人口统计学风险因素。前列腺癌风险较高与以下因素相关:1)与医院对照组相比,长期从事运输或通讯工作(相对风险[RR]=4.92,95%置信区间[CI]:1.18 - 20.5);2)与医院对照组相比,妻子教育水平较低(RR = 1.88,95%CI:1.02 - 3.45);3)与BPH对照组相比,既往无高血压病史(RR = 2.30,95%CI:1.27 - 4.15);4)与BPH和医院对照组相比,有多个姐妹(超过四个)(RR分别为3.82,95%CI:1.35 - 10.8和RR = 2.94,95%CI:1.08 - 8.03);5)与医院对照组相比,体毛浓密(RR = 4.28,95%CI:1.19 - 15.4)。未发现与血型、日常用药、头发、肤色、体型、吸烟习惯、宗教、体重和心理特征有显著关联。