National Diabetes Committee and University Clinic of Emergency Internal Medicine and Toxicology, Skopje, Republic of Macedonia.
National Diabetes Committee and University Clinic of Endocrinology, Diabetes and Metabolic Disorders, Skopje, Republic of Macedonia.
Ann Glob Health. 2015 Nov-Dec;81(6):792-802. doi: 10.1016/j.aogh.2015.12.017.
The Republic of Macedonia (RoM) has experienced a rapid rise in the prevalence of type 2 diabetes (T2D) over the past 2 decades, a period characterized by significant social, political, and economic change. RoM now has one of the highest rates of diabetes in Europe.
To explore the modifiable conditions that may underlie and exacerbate the T2D epidemic; describe the state of diabetes care; and consider improved mechanisms for prevention and treatment, including research priorities, in RoM.
Methods included data mining from reliable sources and collaboration of authors to consider and describe applications of research from outside RoM and to identify evidence-based strategies to reduce the burden of T2D in RoM.
In 2014, the national prevalence of diabetes was 11.44% of the population (20-79 years) of RoM. Per capita caloric intake has increased significantly over the past 2 decades, with the majority of these calories coming from sugar, pork, chicken, beef, and sunflower oil. Excess calories, in the form of nutrient-deficient foods, animal products, and added oils promote insulin resistance and T2D. Tobacco use and lack of physical activity also contribute to the diabetes epidemic. Insulin, especially insulin analogues, are widely available and used to manage diabetes, often over other interventions that are more appropriate for patients with T2D, and more frequently than in other more developed countries, resulting in higher and unsustainable related costs.
A new National eHealth System allows for better identification and monitoring of citizens with diabetes. However, the rapidly growing expense of insulin in the past has been unsustainable. The potential exists for a stronger role for lifestyle interventions in prevention and treatment of T2D. Significant changes in dietary patterns parallel the rise in diabetes prevalence and are likely a leading cause of diabetes and its complications. Research in RoM is needed to determine the impact and acceptability of dietary interventions for prevention and treatment of T2D, as a first step toward reduction of diabetes prevalence and its complications and controlling spiraling health care costs.
过去 20 年来,马其顿共和国(RoM)2 型糖尿病(T2D)的患病率迅速上升,这一时期的特点是社会、政治和经济发生了重大变化。RoM 现在是欧洲糖尿病发病率最高的国家之一。
探讨可能导致 T2D 流行的可改变条件,并阐述糖尿病护理现状,考虑改善预防和治疗的机制,包括 RoM 内的研究重点。
方法包括从可靠来源挖掘数据,作者合作考虑和描述 RoM 以外的研究应用,并确定减少 RoM 中 T2D 负担的循证策略。
2014 年,RoM 全国人口(20-79 岁)的糖尿病患病率为 11.44%。在过去的 20 年里,人均卡路里摄入量显著增加,其中大部分卡路里来自糖、猪肉、鸡肉、牛肉和葵花籽油。过量的卡路里,以营养不足的食物、动物产品和添加油的形式,会导致胰岛素抵抗和 T2D。烟草使用和缺乏身体活动也促成了糖尿病的流行。胰岛素,特别是胰岛素类似物,广泛用于治疗糖尿病,通常比其他更适合 T2D 患者的干预措施更常用,而且比其他更发达的国家更频繁,导致相关费用更高且不可持续。
新的国家电子卫生系统可更好地识别和监测患有糖尿病的公民。然而,过去胰岛素的快速增长成本是不可持续的。在预防和治疗 T2D 方面,生活方式干预可能会发挥更大的作用。饮食模式的显著变化与糖尿病患病率的上升平行,很可能是糖尿病及其并发症的主要原因。RoM 内需要开展研究,以确定饮食干预预防和治疗 T2D 的效果和可接受性,作为降低糖尿病患病率及其并发症以及控制医疗保健费用螺旋式上升的第一步。