英国儿童癌症组织小儿脑肿瘤药物递送研讨会要点
Highlights of Children with Cancer UK's Workshop on Drug Delivery in Paediatric Brain Tumours.
作者信息
Nailor Audrey, Walker David A, Jacques Thomas S, Warren Kathy E, Brem Henry, Kearns Pamela R, Greenwood John, Penny Jeffrey I, Pilkington Geoffrey J, Carcaboso Angel M, Fleischhack Gudrun, Macarthur Donald, Slavc Irene, Meijer Lisethe, Gill Steven, Lowis Stephen, van Vuurden Dannis G, Pearl Monica S, Clifford Steven C, Morrissy Sorana, Ivanov Delyan P, Beccaria Kévin, Gilbertson Richard J, Straathof Karin, Green Jordan J, Smith Stuart, Rahman Ruman, Kilday John-Paul
机构信息
Cancer Intelligence, 154 Cheltenham Road, Bristol, UK BS6 5RL.
Children's Brain Tumour Research Centre, University of Nottingham, Room EE 1833a Nottingham Children's Hospital, Queen's Medical Centre, Nottingham, UK NG7 2UH.
出版信息
Ecancermedicalscience. 2016 Mar 31;10:630. doi: 10.3332/ecancer.2016.630. eCollection 2016.
The first Workshop on Drug Delivery in Paediatric Brain Tumours was hosted in London by the charity Children with Cancer UK. The goals of the workshop were to break down the barriers to treating central nervous system (CNS) tumours in children, leading to new collaborations and further innovations in this under-represented and emotive field. These barriers include the physical delivery challenges presented by the blood-brain barrier, the underpinning reasons for the intractability of CNS cancers, and the practical difficulties of delivering cancer treatment to the brains of children. Novel techniques for overcoming these problems were discussed, new models brought forth, and experiences compared.
首届儿童脑肿瘤药物递送研讨会由英国慈善机构“患癌儿童”在伦敦主办。该研讨会的目标是消除儿童中枢神经系统（CNS）肿瘤治疗中的障碍，从而在这个研究较少且令人关注的领域促成新的合作并推动进一步创新。这些障碍包括血脑屏障带来的物理递送挑战、中枢神经系统癌症难以治疗的根本原因，以及将癌症治疗递送至儿童脑部的实际困难。会上讨论了克服这些问题的新技术，提出了新模型，并比较了相关经验。
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