Lang Julien, Faure Denis
a Institute for Integrative Biology of the Cell (I2BC), CNRS CEA Univ. Paris-Sud, Université Paris-Saclay , Avenue de la Terrasse, Gif-sur-Yvette , France.
Plant Signal Behav. 2016 May 3;11(5):e1178440. doi: 10.1080/15592324.2016.1178440.
Accumulation of amino acids is a common plant response to several biotic and abiotic stresses, even if the roles of these accumulations remain often poorly understood. In a recent study we measured the levels of different amino acids in tumors of Arabidopsis thaliana induced by the phytopathogen Agrobacterium tumefaciens and correlated these data with changes of gene expressions in both organisms. This led to the demonstration that the non-protein amino acid GABA plays an important role for the adaptation of the bacteria to the plant tumor environment, and especially in the control of the virulent Ti plasmid dissemination. Here we present a model that describes how different GABA:proline ratios in the A. thaliana host may have different impacts on the conjugation of A. tumefaciens Ti plasmid, and advance the view that the amino acid metabolism of plant hosts could be critical for the propagation of the virulence genes in A. tumefaciens populations.
氨基酸积累是植物对多种生物和非生物胁迫的常见反应，尽管这些积累的作用通常仍知之甚少。在最近的一项研究中，我们测量了由植物病原体根癌农杆菌诱导的拟南芥肿瘤中不同氨基酸的水平，并将这些数据与两种生物体中基因表达的变化相关联。这表明非蛋白质氨基酸GABA在细菌适应植物肿瘤环境中起着重要作用，特别是在控制毒性Ti质粒传播方面。在这里，我们提出了一个模型，描述了拟南芥宿主中不同的GABA:脯氨酸比率如何对根癌农杆菌Ti质粒的接合产生不同影响，并提出植物宿主的氨基酸代谢可能对根癌农杆菌群体中毒力基因的传播至关重要的观点。
