Cameron Jameason D, Sigal Ronald J, Kenny Glen P, Alberga Angela S, Prud'homme Denis, Phillips Penny, Doucette Steve, Goldfield Gary
a Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
b University of Ottawa, Ottawa, ON, Canada.
Appl Physiol Nutr Metab. 2016 Jun;41(6):611-7. doi: 10.1139/apnm-2015-0479. Epub 2016 Feb 8.
There has been renewed interest in examining the relationship between specific components of energy expenditure and the overall influence on energy intake (EI). The purpose of this cross-sectional analysis was to determine the strongest metabolic and anthropometric predictors of EI. It was hypothesized that resting metabolic rate (RMR) and skeletal muscle mass would be the strongest predictors of EI in a sample of overweight and obese adolescents. 304 post-pubertal adolescents (91 boys, 213 girls) aged 16.1 (±1.4) years with body mass index at or above the 95th percentile for age and sex OR at or above the 85th percentile plus an additional diabetes risk factor were measured for body weight, RMR (kcal/day) by indirect calorimetry, body composition by magnetic resonance imaging (fat free mass (FFM), skeletal muscle mass, fat mass (FM), and percentage body fat), and EI (kcal/day) using 3 day food records. Body weight, RMR, FFM, skeletal muscle mass, and FM were all significantly correlated with EI (p < 0.005). After adjusting the model for age, sex, height, and physical activity, only FFM (β = 21.9, p = 0.007) and skeletal muscle mass (β = 25.8, p = 0.02) remained as significant predictors of EI. FFM and skeletal muscle mass also predicted dietary protein and fat intake (p < 0.05), but not carbohydrate intake. In conclusion, with skeletal muscle mass being the best predictor of EI, our results support the hypothesis that the magnitude of the body's lean tissue is related to absolute levels of EI in a sample of inactive adolescents with obesity.
人们对研究能量消耗的特定组成部分与能量摄入（EI）的总体影响之间的关系重新产生了兴趣。本横断面分析的目的是确定EI最强的代谢和人体测量学预测因素。研究假设，在超重和肥胖青少年样本中，静息代谢率（RMR）和骨骼肌质量将是EI最强的预测因素。对304名年龄在16.1（±1.4）岁的青春期后青少年（91名男孩，213名女孩）进行了测量，这些青少年的体重指数处于年龄和性别的第95百分位数及以上，或处于第85百分位数及以上并伴有额外的糖尿病风险因素，测量内容包括体重、通过间接测热法测得的RMR（千卡/天）、通过磁共振成像测得的身体成分（去脂体重（FFM）、骨骼肌质量、脂肪量（FM）和体脂百分比），以及使用3天食物记录测得的EI（千卡/天）。体重、RMR、FFM、骨骼肌质量和FM均与EI显著相关（p < 0.005）。在对年龄、性别、身高和身体活动进行模型调整后，只有FFM（β = 21.9，p = 0.007）和骨骼肌质量（β = 25.8，p = 0.02）仍然是EI的显著预测因素。FFM和骨骼肌质量还预测了膳食蛋白质和脂肪摄入量（p < 0.05），但未预测碳水化合物摄入量。总之，骨骼肌质量是EI的最佳预测因素，我们的结果支持了这样的假设，即在不活动的肥胖青少年样本中，身体瘦组织的量与EI的绝对水平相关。
