Vasyukova O V, Okorokov P L, Kasyanova Yu V, Bezlepkina O B
Endocrinology Research Center.
Probl Endokrinol (Mosk). 2021 Oct 14;67(5):4-10. doi: 10.14341/probl12830.
Obesity is a consequence of chronic energy imbalance when energy intake constantly exceeds expenditure, which leads to excess white adipose tissue accumulation. Effective treatment of obesity requires accurate measure of calories intake and expenditure, as well as related behavior to understand how energy homeostasis is regulated and evaluate the effectiveness of the measures taken. The greatest interest is to study features of energy metabolism in various forms of obesity. It is necessary to create an evidence-based, personalized approach to diet therapy and to increase the effectiveness of weight loss measures. Modern studies have shown that the use of indirect calorimetry in obesity treatment programs leads to greater weight loss compared to traditional diet therapy planning based on calculated formulas.
肥胖是能量长期失衡的结果，即能量摄入持续超过能量消耗，这会导致白色脂肪组织过度堆积。有效治疗肥胖需要精确测量卡路里的摄入与消耗，以及了解相关行为，以掌握能量稳态的调节方式并评估所采取措施的有效性。最受关注的是研究各种肥胖形式下的能量代谢特征。有必要制定基于证据的个性化饮食治疗方法，并提高减肥措施的有效性。现代研究表明，在肥胖治疗方案中使用间接测热法比基于计算公式的传统饮食治疗计划能带来更多的体重减轻。
