He Zhao-yang, Jiao Qing-ling, Miao Yang, Sun Yan
Anesthesiology department, Maternal and Child Health Hospital of Zhengzhou City, Zhengzhou City, Henan Province, China.
Pak J Pharm Sci. 2016 Mar;29(2 Suppl):707-9.
This study aimed to explore the effect of ropivacaine combined with sufentanil on maternal lactation and infant, which were used by different anesthesia method for painless childbirth. 284 cases of voluntary acceptance of painless childbirth pregnant were involved in this study and divided into control group and observation group. Ropivacaine combined with sufentanil epidural anesthesia (CEA) was used in the control group, and ropivacaine combined with sufentanil epidural block (CSEA) anesthesia was used in the observation group. Meanwhile, maternal colostrum time, postpartum lactation and neonatal Apgar score were analyzed. The colostrum time of the observation group was significantly shorter than that in the control group and the lactation quantity of 24 h was significantly higher than that in the control group. There were significant differences between the control and the observation groups (P<0.05). However, there was no significant difference in neonatal Apgar score (p>0.05). Combined spinal epidural anesthesia of ropivacaine combined with sufentanil is more conducive to the early postpartum lactation compared with epidural anesthesia. And both of the two ways of anesthesia had no effect on the neonatal Apgar score.
本研究旨在探讨不同麻醉方法用于无痛分娩时,罗哌卡因联合舒芬太尼对产妇泌乳及婴儿的影响。本研究纳入284例自愿接受无痛分娩的孕妇,分为对照组和观察组。对照组采用罗哌卡因联合舒芬太尼硬膜外麻醉(CEA),观察组采用罗哌卡因联合舒芬太尼腰硬联合麻醉(CSEA)。同时,分析产妇初乳时间、产后泌乳情况及新生儿Apgar评分。观察组初乳时间显著短于对照组,24小时泌乳量显著高于对照组。对照组和观察组之间存在显著差异(P<0.05)。然而,新生儿Apgar评分无显著差异(P>0.05)。与硬膜外麻醉相比,罗哌卡因联合舒芬太尼腰硬联合麻醉更有利于产后早期泌乳。两种麻醉方式对新生儿Apgar评分均无影响。