Hill Travis C, Tanweer Omar, Thomas Cheddhi, Engler John, Shapiro Maksim, Becske Tibor, Huang Paul P
New York University School of Medicine, New York, NY, USA.
Department of Neurosurgery, New York University School of Medicine, New York, NY, USA.
J Cerebrovasc Endovasc Neurosurg. 2016 Mar;18(1):42-7. doi: 10.7461/jcen.2016.18.1.42. Epub 2016 Mar 31.
Rupture of isolated posterior spinal artery (PSA) aneurysms is a rare cause of subarachnoid hemorrhage (SAH) that presents unique diagnostic challenges owing to a nuanced clinical presentation. Here, we report on the diagnosis and management of the first known case of an isolated PSA aneurysm in the context of leukocytoclastic vasculitis. A 53-year-old male presented to an outside institution with acute bilateral lower extremity paralysis 9 days after admission for recurrent cellulitis. Early magnetic resonance imaging was read as negative and repeat imaging 15 days after presentation revealed SAH and a compressive spinal subdural hematoma. Angiography identified a PSA aneurysm at T9, as well as other areas suspicious for inflammatory or post-hemorrhagic reactive changes. The patient underwent a multilevel laminectomy for clot evacuation and aneurysm resection to prevent future hemorrhage and to establish a diagnosis. The postoperative course was complicated by medical issues and led to the diagnosis of leukocytoclastic vasculitis that may have predisposed the patient to aneurysm development. Literature review reveals greater mortality for cervical lesions than thoracolumbar lesions and that the presence of meningitic symptoms portents better functional outcome than symptoms of cord compression. The outcome obtained in this case is consistent with outcomes reported in the literature.
孤立性脊髓后动脉(PSA)动脉瘤破裂是蛛网膜下腔出血(SAH)的罕见原因,因其临床表现细微而带来独特的诊断挑战。在此,我们报告了在白细胞破碎性血管炎背景下首例已知的孤立性PSA动脉瘤的诊断与治疗情况。一名53岁男性因复发性蜂窝织炎入院9天后,在外院出现急性双侧下肢瘫痪。早期磁共振成像检查结果为阴性,就诊15天后复查成像显示有SAH和压迫性脊髓硬膜下血肿。血管造影显示T9水平有一个PSA动脉瘤,以及其他可疑为炎症或出血后反应性改变的区域。患者接受了多级椎板切除术以清除血块并切除动脉瘤,以防止未来出血并明确诊断。术后病程因医疗问题而复杂化,最终诊断为白细胞破碎性血管炎,这可能是患者发生动脉瘤的诱因。文献综述显示,颈椎病变的死亡率高于胸腰椎病变,且脑膜症状患者的功能预后比脊髓压迫症状患者更好。本病例的治疗结果与文献报道的结果一致。