Malandraki Georgia A, Markaki Vasiliki, Georgopoulos Voula C, Psychogios Loukia, Nanas Serafim
Am J Speech Lang Pathol. 2016 May 1;25(2):150-6. doi: 10.1044/2015_AJSLP-14-0069.
This study provided preliminary data on the occurrence and impact of postextubation dysphagia in the largest Greek step-down intensive care unit (ICU) over 2 years.
A retrospective observational cohort study of patients referred for swallowing assessment postextubation was conducted from November, 2011, to August, 2013.
Of the 357 patients admitted to the unit during this period, 87, aged 55.8 ± 18.1 years (61 male, 26 female), were referred and evaluated. Of these, 2.3% were found to have no dysphagia, and 21.8% and 75.9% were diagnosed with mild and moderate/severe dysphagia, respectively. Across severity levels, 23% of patients in the unit were found to have dysphagia. Patients with moderate/severe dysphagia were more likely to have had prolonged intubation (> 48 hr; p = .02) and exhibit signs of aspiration (p = .002) than those with no or mild dysphagia. Prolonged intubation was associated with increased likelihood of moderate/severe dysphagia by a factor of 12 (p = .042, odds ratio = 12.355) compared to short intubation. Moderate/severe dysphagia was correlated with pneumonia (p = .02), feeding tube placement (p = .004) and in-hospital mortality (p = .034).
In this sample, moderate/severe dysphagia was correlated with prolonged intubation, and was found to increase the risk for pneumonia and in-hospital mortality. Our results suggest the importance of early dysphagia management in critical patients in Greece and globally.
本研究提供了希腊最大的逐步降级重症监护病房(ICU)在两年多时间里拔管后吞咽困难的发生率和影响的初步数据。
对2011年11月至2013年8月期间接受拔管后吞咽评估的患者进行回顾性观察队列研究。
在此期间入住该病房的357例患者中,87例(年龄55.8±18.1岁,男性61例,女性26例)接受了转诊和评估。其中,2.3%被发现没有吞咽困难,21.8%和75.9%分别被诊断为轻度和中度/重度吞咽困难。在各个严重程度级别中,该病房23%的患者被发现有吞咽困难。与无吞咽困难或轻度吞咽困难的患者相比,中度/重度吞咽困难的患者更有可能插管时间延长(>48小时;p=0.02)并出现误吸迹象(p=0.002)。与短时间插管相比,插管时间延长使中度/重度吞咽困难的可能性增加了12倍(p=0.042,优势比=12.355)。中度/重度吞咽困难与肺炎(p=0.02)、放置饲管(p=0.004)和住院死亡率(p=0.034)相关。
在本样本中,中度/重度吞咽困难与插管时间延长相关,并被发现会增加肺炎和住院死亡率的风险。我们的结果表明,在希腊乃至全球,对危重症患者进行早期吞咽困难管理具有重要意义。