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一名5岁免疫功能正常儿童中,表现为脑膜瘤的轴外原发性非霍奇金中枢神经系统淋巴瘤:一种罕见病例。

Extra-axial primary non-Hodgkin's CNS lymphoma mimicking meningioma, in a 5-year-old immunocompetent child: a rare entity.

作者信息

Bhaskar Mukesh Kumar, Ojha Balkrishna, Jaiswal Manish, Sagar Mala

机构信息

Department of Neurosurgery, King George's Medical University, Lucknow, Uttar Pradesh, India.

Department of Neurosurgery, CSM Medical University, Lucknow, Uttar Pradesh, India.

出版信息

BMJ Case Rep. 2016 Apr 26;2016:bcr2016215119. doi: 10.1136/bcr-2016-215119.

Abstract

We describe a case of a 5-year-old immunocompetent girl who presented with features of raised intracranial pressure with left eye ptosis of 1-month duration. CT scan and MRI of the brain showed an extra-axial, intensely contrast enhancing lesion in the left temporoparieto-occipital region, consistent with meningioma. On open tissue biopsy and immunohistochemistry staining, a diagnosis of B cell non-Hodgkin's lymphoma was made. Six cycles of chemotherapy with cyclophosphamide, adriamycin, vincristine and prednisolone regimen were given and showed a good clinical outcome without any recurrence during follow-up of 5 months.

摘要

我们描述了一例5岁免疫功能正常的女孩,她出现颅内压升高伴左眼上睑下垂1个月。脑部CT扫描和MRI显示左侧颞顶枕区有一个轴外强化明显的病变,符合脑膜瘤表现。经手术组织活检和免疫组化染色,诊断为B细胞非霍奇金淋巴瘤。给予了六个周期的环磷酰胺、阿霉素、长春新碱和泼尼松龙方案化疗,在5个月的随访期间临床效果良好,无任何复发。

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