Sosin Michael, Ceradini Daniel J, Hazen Alexes, Levine Jamie P, Staffenberg David A, Saadeh Pierre B, Flores Roberto L, Brecht Lawrence E, Bernstein G Leslie, Rodriguez Eduardo D
New York, N.Y.
From the Hansjörg Wyss Department of Plastic Surgery, New York University Langone Medical Center.
Plast Reconstr Surg. 2016 May;137(5):1569-1581. doi: 10.1097/PRS.0000000000002122.
The application of aesthetic, craniofacial, and microsurgical principles in the execution of face transplantation may improve outcomes. Optimal soft-tissue face transplantation can be achieved by incorporating subunit facial skeletal replacement and subsequent tissue resuspension. The purpose of this study was to establish a reconstructive solution for a full face and scalp burn and to evaluate outcome precision and consistency.
Seven mock face transplants (14 cadavers) were completed in the span of 1 year. Components of the vascularized composite allograft included the eyelids, nose, lips, facial muscles, oral mucosa, total scalp, and ears; and skeletal subunits of the zygoma, nasal bone, and genial segment. Virtual surgical planning was used for osteotomy selection, and to evaluate postoperative precision of hard- and soft-tissue elements.
Each transplant experience decreased each subsequent transplant surgical time. Prefabricated cutting guides facilitated a faster dissection of both donor and recipient tissue, requiring minimal alteration to the allograft for proper fixation of bony segments during inset. Regardless of donor-to-recipient size discrepancy, ample soft tissue was available to achieve tension-free allograft inset. Differences between virtual transplant simulation and posttransplant measurements were minimal or insignificant, supporting replicable and precise outcomes.
This facial transplant model was designed to optimize reconstruction of extensive soft-tissue defects of the craniofacial region representative of electrical, thermal, and chemical burns, by incorporating skeletal subunits within the allograft. The implementation of aesthetic, craniofacial, and microsurgical principles and computer-assisted technology improves surgical precision, decreases operative time, and may optimize function.
在面部移植手术中应用美学、颅面外科和显微外科原则可能会改善手术效果。通过纳入面部骨骼亚单位置换及随后的组织重新悬吊,可实现最佳的软组织面部移植。本研究的目的是建立一种针对全脸和头皮烧伤的重建方案,并评估结果的精确性和一致性。
在1年的时间内完成了7次模拟面部移植手术(14具尸体)。带血管复合组织异体移植的组成部分包括眼睑、鼻子、嘴唇、面部肌肉、口腔黏膜、整个头皮和耳朵;以及颧骨、鼻骨和颏部的骨骼亚单位。采用虚拟手术规划来选择截骨方式,并评估术后硬组织和软组织成分的精确性。
每次移植经验都缩短了随后每次移植手术的时间。预制切割导板有助于更快地解剖供体和受体组织,在植入过程中对异体移植物进行最小程度的改动即可实现骨段的正确固定。无论供体与受体的大小差异如何,都有足够的软组织可实现无张力的异体移植物植入。虚拟移植模拟与移植后测量之间的差异极小或不显著,支持了可重复和精确的手术效果。
该面部移植模型旨在通过在异体移植物中纳入骨骼亚单位,优化对代表电烧伤、热烧伤和化学烧伤的颅面部广泛软组织缺损的重建。美学原则、颅面外科原则和显微外科原则以及计算机辅助技术的应用提高了手术精确性,缩短了手术时间,并可能优化功能。