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一种表观分子量为8千道尔顿的细粒棘球绦虫特异性诊断抗原。

A specific diagnostic antigen of Echinococcus granulosus with an apparent molecular weight of 8 kDA.

作者信息

Maddison S E, Slemenda S B, Schantz P M, Fried J A, Wilson M, Tsang V C

机构信息

Division of Parasitic Diseases, Centers for Disease Control, Atlanta, Georgia.

出版信息

Am J Trop Med Hyg. 1989 Apr;40(4):377-83. doi: 10.4269/ajtmh.1989.40.377.

DOI:10.4269/ajtmh.1989.40.377
PMID:2712196
Abstract

An echinococcus antigen with an apparent molecular weight of 8 kDa was identified as diagnostically important. An immunoblot assay using this antigen was 91% sensitive for surgically confirmed Echinococcus granulosus hydatid disease of the liver. Specificity was 100% for echinococcosis. Marked cross-reactivity was observed with serum specimens from patients with E. multilocularis and E. vogeli infections. The 8 kDa component was not related to the widely recognized echinococcus antigen 5.

摘要

一种表观分子量为8 kDa的棘球蚴抗原被确定具有诊断重要性。使用该抗原的免疫印迹分析对手术确诊的肝细粒棘球绦虫包虫病的敏感性为91%。对棘球蚴病的特异性为100%。观察到与多房棘球绦虫和伏氏棘球绦虫感染患者的血清标本有明显的交叉反应。8 kDa成分与广泛认可的棘球蚴抗原5无关。

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