彼得·卡利斯：一位杰出的脂质生物物理学家、药物递送科学家、教育家和企业家。
Pieter Cullis: an outstanding lipid biophysicist, drug delivery scientist, educator, and entrepreneur.
作者信息
Huang Leaf, Miao Lei
机构信息
a Division of Molecular Pharmaceutics , Eshelman School of Pharmacy, University of North Carolina at Chapel Hill , Chapel Hill , NC , USA.
出版信息
J Drug Target. 2016 Nov;24(9):762-764. doi: 10.3109/1061186X.2016.1172590. Epub 2016 Apr 27.
Abstract
There are much said about Pieter Cullis in this special volume honoring him. He was the pioneer to study the role of hexagonal HII phase in membrane fusion and the one who applied this concept for the design of lipid nanoparticles. He was also the first to utilize remote loading techniques for the delivery of amphipathic bases. At the same time, he is a tremendous entrepreneur and an excellent mentor. He is, without doubt, an exceptional scientist and set us an excellent model to follow.
摘要
在这本向彼得·卡利斯致敬的特刊中有很多关于他的介绍。他是研究六方HII相在膜融合中作用的先驱，也是将这一概念应用于脂质纳米颗粒设计的人。他还是第一个利用远程加载技术来递送两亲性碱基的人。同时，他是一位了不起的企业家和优秀的导师。毫无疑问，他是一位杰出的科学家，为我们树立了一个优秀的榜样。
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本文引用的文献
1
Remote loading of aloe emodin in gemini-based cationic liposomes.基于双子星的阳离子脂质体中芦荟大黄素的远程负载
Langmuir. 2015;31(1):76-82. doi: 10.1021/la5038074. Epub 2014 Dec 23.
2
Doxil®--the first FDA-approved nano-drug: lessons learned.多西紫杉醇脂质体（Doxil®）——首个获美国 FDA 批准的纳米药物：经验教训。
J Control Release. 2012 Jun 10;160(2):117-34. doi: 10.1016/j.jconrel.2012.03.020. Epub 2012 Mar 29.
3
siRNA LNCs--a novel platform of lipid nanocapsules for systemic siRNA administration.siRNA LNCs——一种新型的脂质纳米胶囊平台，用于系统的 siRNA 给药。
Eur J Pharm Biopharm. 2012 Jun;81(2):448-52. doi: 10.1016/j.ejpb.2012.02.010. Epub 2012 Feb 21.
4
Characterization of PEGylated nanoliposomes co-remotely loaded with topotecan and vincristine: relating structure and pharmacokinetics to therapeutic efficacy.聚乙二醇化纳米脂质体共载拓扑替康和长春新碱的表征：结构与药代动力学与治疗效果的关系。
J Control Release. 2012 Jun 10;160(2):281-9. doi: 10.1016/j.jconrel.2011.10.003. Epub 2011 Oct 12.
5
Rational design of cationic lipids for siRNA delivery.阳离子脂质体的 siRNA 递呈的合理设计。
Nat Biotechnol. 2010 Feb;28(2):172-6. doi: 10.1038/nbt.1602. Epub 2010 Jan 17.
6
On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids.关于阳离子脂质促进多核酸细胞内递送的机制
Gene Ther. 2001 Aug;8(15):1188-96. doi: 10.1038/sj.gt.3301506.
7
Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures.使用可电离氨基脂质将反义寡核苷酸高效封装于脂质囊泡中：新型小多层囊泡结构的形成
Biochim Biophys Acta. 2001 Feb 9;1510(1-2):152-66. doi: 10.1016/s0005-2736(00)00343-6.
8
Roles of lipid polymorphism in intracellular delivery.脂质多态性在细胞内递送中的作用。
Adv Drug Deliv Rev. 2001 Apr 25;47(2-3):139-48. doi: 10.1016/s0169-409x(01)00103-x.
9
Tunable pH-sensitive liposomes composed of mixtures of cationic and anionic lipids.由阳离子脂质和阴离子脂质混合物组成的可调节pH敏感脂质体。
Biophys J. 2000 Sep;79(3):1438-46. doi: 10.1016/S0006-3495(00)76395-8.
10
Factors influencing uptake and retention of amino-containing drugs in large unilamellar vesicles exhibiting transmembrane pH gradients.影响含氨基药物在呈现跨膜pH梯度的大单层囊泡中的摄取和保留的因素。
Biochim Biophys Acta. 1999 Jan 12;1416(1-2):1-10. doi: 10.1016/s0005-2736(98)00204-1.
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