Tadic Marijana, Cuspidi Cesare, Vukomanovic Vladan, Kocijancic Vesna, Celic Vera
a Department of Cardiology , University Clinical Hospital Center "Dr Dragisa Misovic - Dedinje" , Belgrade , Serbia ;
b Faculty of Medicine , Belgrade , Serbia ;
Blood Press. 2016 Oct;25(5):292-7. doi: 10.3109/08037051.2016.1172868. Epub 2016 Apr 28.
We sought to evaluate right ventricular (RV) structure and function in hypertensive patients with various left ventricular (LV) geometric patterns using an updated classification for LV geometry.
This cross-sectional study included 232 hypertensive subjects. All the subjects underwent complete two-dimensional (2D) and three-dimensional (3D) echocardiographic examination. Using LV mass index, LV end-diastolic diameter and relative wall thickness, according to the updated classification, all subjects were divided into six different groups: normal LV geometry, concentric remodeling, eccentric LV hypertrophy (LVH), concentric, dilated, and concentric-dilated LVH.
RV wall thickness was increased in concentric and concentric-dilated LVH compared with normal LV geometry and LV concentric remodeling. RV longitudinal function was reduced in concentric and concentric-dilated patients compared with other hypertensive groups. 3D RV volumes were significantly higher in eccentric, dilated, and concentric-dilated LVH hypertensive subjects. Conversely, 3D RV ejection fraction was lower in these groups.
RV longitudinal myocardial function and 3D RV function are significantly influenced by LV geometry in hypertensive patients. RV remodeling is the most pronounced in the patients with concentric, dilated, and concentric-dilated LVH geometric patterns.
我们试图使用更新后的左心室几何形态分类法，评估不同左心室几何形态模式的高血压患者的右心室（RV）结构和功能。
这项横断面研究纳入了232名高血压受试者。所有受试者均接受了完整的二维（2D）和三维（3D）超声心动图检查。根据更新后的分类法，利用左心室质量指数、左心室舒张末期直径和相对壁厚度，将所有受试者分为六个不同组：正常左心室几何形态、向心性重塑、离心性左心室肥厚（LVH）、向心性、扩张性和向心性扩张性LVH。
与正常左心室几何形态和左心室向心性重塑相比，向心性和向心性扩张性LVH患者的右心室壁厚度增加。与其他高血压组相比，向心性和向心性扩张性患者的右心室纵向功能降低。在离心性、扩张性和向心性扩张性LVH高血压受试者中，三维右心室容积显著更高。相反，这些组中的三维右心室射血分数较低。
高血压患者的右心室纵向心肌功能和三维右心室功能受左心室几何形态的显著影响。在向心性、扩张性和向心性扩张性LVH几何形态模式的患者中，右心室重塑最为明显。
